Protein Alignment hrm and slc16a1a

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001243569.1
• Gene: slc16a1a / 100534752
• ZFINID: ZDB-GENE-110408-16
• Length: 461
• Species: Danio rerio
• Alignment Length: 635
• Identity: 137/635 - (21%)
• Similarity: 233/635 - (36%)
• Gaps: 218/635 - (34%)

  Fly    49 PPDGGWGWLVLLGSCLT---NILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGP 110
            ||:|||||.|:||:.::   :...|   ||..|.|.|....||::.::.:||.::...:....||
Zfish    13 PPEGGWGWAVVLGAFISIGFSYAFP---KSITVFFKEIEVIFNATSSQVSWISSIMLAVMYGGGP 74

  Fly   111 VSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYF 175
            |||||..||..|.:.:|||..:..|:|.:.:.:::|.||...||:.|:|...:..|.:.::..||
Zfish    75 VSSILVNKYGSRPIMILGGCLSGAGLIAASFCNTVEGLYFCVGVVGGLGLAFNLNPALTMIGKYF 139

  Fly   176 AKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVR 240
            .|.|.:|||:.::||.:....|.||..|..:.:|:.||.||:||:.||..||.....|:.
Zfish   140 YKKRPIANGIAMAGSPVFLSTLAPLNTWFFDQFGWRGSFLILGGLLLNCCVAGSLMRPIG----- 199

  Fly   241 VPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSAS 305
                                          ||.:||.|
Zfish   200 ------------------------------PKPQPAVK--------------------------- 207

  Fly   306 AAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSK 370
                      .|...||:::..|.|.:           :|.
Zfish   208 ----------ADNSNSRAKERKTVVEV-----------ING------------------------ 227

  Fly   371 SRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDAR 435
                                                                             
Zfish   228 ----------------------------------------------------------------- 227

  Fly   436 GQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVS 500
                      |.||:|.|...:|:.|:.|........:.::.|.::.:::...:..:|:|||:::
Zfish   228 ----------FIDLTLFKHRGFLLYLLGNVVMFFGLFSPLVFLSNYAKSKQIPREKAAFLLSILA 282

  Fly   501 ATDLIGRIGGSALSDMGYIPKT-W-------YFVGGLSISGLSLALLPFAWTYSSVCFWCALFGL 557
            ..|::.|      ..||.:..| |       :|...:.::|:...|.|.:..|:....:...||.
Zfish   283 FVDMVAR------PSMGIVANTKWVRPRVQHFFAASILLNGVCHLLAPLSTDYTGFVIYAIFFGF 341

  Fly   558 ASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTL 622
            |.|....:....:.|::|.:|.:|:.|:...|.....|:||||...:.:..:||...:...|:.|
Zfish   342 AFGWLSSVLFETLMDLVGAQRFSSAVGLVTIVECGPVLLGPPLLGKFNDIYHDYKYTYMGCGIVL 406

  Fly   623 LAGASLWSFMPW-IN-----------RRKANAEEQLDAQIE---KAAVDS 657
            |.| ||:.|:.. ||           .:|||..:....::|   |||.|:
Zfish   407 LIG-SLFLFVGMGINYKLLEREAKEESKKANQHDDPGKEVEEALKAAEDN 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	133/629 (21%)
		MFS	59..>234	CDD:119392	59/177 (33%)
		MFS	<449..633	CDD:119392	46/191 (24%)
slc16a1a	NP_001243569.1	2A0113	6..446	CDD:273325	132/624 (21%)
		MFS	20..415	CDD:119392	120/586 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm6360
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.820