Protein Alignment hrm and slc16a2

DIOPT Version :10

• Sequence 1: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: XP_031747020.1
• Gene: slc16a2 / 100494635
• XenbaseID: XB-GENE-980579
• Length: 499
• Species: Xenopus tropicalis
• Alignment Length: 622
• Identity: 123/622 - (19%)
• Similarity: 212/622 - (34%)
• Gaps: 214/622 - (34%)

  Fly    50 PDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPT-----KAAWIPALCYFLYSSLG 109
            |:||:||:|:|.:...:..|.|...|||:::.......:.:..     |.||:.:|...:.....
 Frog    52 PEGGFGWVVVLAATWCSGSIFGIQNSFGIIYVMLQGEMDGTEEQGMDFKTAWVGSLAMGMIFFCS 116

  Fly   110 PVSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSY 174
            ||.||.:.:...|..:..|.|.|.:|::.|.:..|:...|.:||:|.|.|...:|.|::.|:..|
 Frog   117 PVVSIFTDRLGCRKTSSGGAALAFIGLLSSSFTKSLGVRYFTYGILFGCGCSFAFQPSLVILGHY 181

  Fly   175 FAKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGI-----TLNVFVAALFYEPV 234
            |.|..||.||:...||.:.::.||.||:             :|||.     |..|....:|.:
 Frog   182 FKKRLGLVNGIVAGGSCVFTMCLPFLLK-------------MMGGAIGLQHTFQVLSVFMFIQ-- 231

  Fly   235 EQHMVRVPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQ 299
                                  |.:.:.|              |||||   ||.
 Frog   232 ----------------------IFLSLTF--------------KPLLP---PPV----------- 246

  Fly   300 FVRSASAAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLT 364
                              :|.....|::                            |||
 Frog   247 ------------------DFSKEKEKVA----------------------------GRS------ 259

  Fly   365 LRNSSKSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSY 429
                                                                             
 Frog   260 ----------------------------------------------------------------- 259

  Fly   430 ADVDARGQAQQ--PQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLS 492
                   :|||  ....|:|::.:.:...|.:..:..:|..:.|....:.|..|.|.| |.::..
 Frog   260 -------KAQQCMAHTRKYFNMQVFRRKTYTIWALGIATTVLGYFVPYVHLIKFVEQR-FKENTK 316

  Fly   493 AYLLSV-VSATDLIGRIGGSALSDMGYIP---KTWYFVGGLSISGLSLALLPFAWTYSSVCFWCA 553
            .::|.| :.||..|||:....:.|.  ||   |.:..|....:.|:...:||....:.||...|.
 Frog   317 EWVLLVCIGATSGIGRLASGRIGDS--IPGLKKIYLQVASFLLLGILSMMLPLCQVFESVIVVCL 379

  Fly   554 LFGLASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQL---VGPPLCNYWFEAVNDYNPLF 615
            ..||..|..:.:.:.|..:::|..:.:.:.|   :|.||:.:   .|||:.....:....|:..|
 Frog   380 FLGLCDGFLISMMSPIAFELVGPMQASQAIG---YVLGLMSIPMTAGPPIAGLLRDYCGSYDLAF 441

  Fly   616 HALGLTLLAGASLWSFMPWINRRKANAEEQLDAQIEK 652
            :..|:..|.||.:...:|.::.|....:.|::.:.||
 Frog   442 YLAGIPPLIGAMVLLSVPLVHERDLKKKRQMEEEKEK 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	51/185 (28%)
		MFS	<451..633	CDD:475125	44/188 (23%)
slc16a2	XP_031747020.1	MFS_MCT8	57..459	CDD:341023	115/596 (19%)