Protein Alignment hrm and slc16a10

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: XP_012819019.1
• Gene: slc16a10 / 100488837
• XenbaseID: XB-GENE-1012623
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 676
• Identity: 136/676 - (20%)
• Similarity: 234/676 - (34%)
• Gaps: 231/676 - (34%)

  Fly     9 SQNASKINQKDHKPNG------------NTNESRHKTVSLINKKDDKEYDLVPPDGGWGWLVLLG 61
            ::..|.:|..:.|.||            ..|:.:....:..:..:|||:.  ||:|||||:|::.
 Frog    19 NEEMSPLNSVEGKENGEMDPVSIEEEKLKANDEKDPEAAKESALEDKEFQ--PPEGGWGWMVMVA 81

  Fly    62 SCLTNILIPGTIKSFGVLFSEFTDAFNSSPT-----KAAWIPALCYFLYSSLGPVSSILSVKYSY 121
            :...|..:.|...:.||||....:.|.|...     |.||:.:|...:.....||.||.:..:..
 Frog    82 AMWCNGSVFGIQNACGVLFVSLIEEFGSKDDTEMTFKTAWVNSLSMGMIFFCSPVVSIFTDIFGC 146

  Fly   122 RTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLRGLANGLC 186
            |....:|.|...:|::.|.:.||:|.||.:||:|...|...::.|::.|:..||.|..||.||:.
 Frog   147 RKTATVGAAVGIVGLLSSSFVSSLEPLYFTYGILFACGCSFAYQPSLVILGHYFKKRLGLVNGIV 211

  Fly   187 ISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPRARQALENI 251
            .:||:|.::.||.:||:||:......:..::..:...:|:|...|:|:      ||| |..||
 Frog   212 TAGSSLFTVSLPFVLRFLLDKIRLFKTLQVLCILMFILFLAGFTYKPL------VPR-RSNLE-- 267

  Fly   252 PEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAVVQSYSKSG 316
                                                                        :.|:|
 Frog   268 ------------------------------------------------------------FKKNG 272

  Fly   317 DEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSS---LYAVPEGRSSSNKLTLRNSSKSRLSKRSP 378
                        ..|.|..|:.|......|:|.   .:.:|
 Frog   273 ------------KFRCPSVNKLFNFSIFKSRSYCLWAFGIP------------------------ 301

  Fly   379 STSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQAQQPQR 443
             .:.|.|. .||             .||         ..|..:..|:|
 Frog   302 -AALFGYF-VPY-------------VHL---------MNHVRERLGED----------------- 325

  Fly   444 SKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATDLIGRI 508
                    :|:.:                                      ||..:..|..:||:
 Frog   326 --------VKEEV--------------------------------------LLLCIGVTSGVGRL 344

  Fly   509 GGSALSDMGYIP---KTWYFVGGLSISGLSLALLPFAWTYSSVCFWCALFGLASGIYVGITAVIM 570
            ....::|  |||   |.:..|......||...::|....:..:...|...||..|.::.|.|.|.
 Frog   345 IFGRVAD--YIPGVKKVYLQVVSFFFIGLMSMMIPLCHNFGGLIAVCLFMGLFDGCFICIMAPIA 407

  Fly   571 ADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGASLWSFMPWI 635
            .:::|.|.::.:.|..|....:...||||:.....:.:..|:..|:..|:..:.|..:...:|||
 Frog   408 FELVGPENVSQAIGFLLGFMSIPMTVGPPIAGILHDRLGSYDVAFYLAGIPPIIGGIILCLIPWI 472

  Fly   636 NRR---------KANAEEQLDAQIEK 652
            ::|         ..:|||::   :||
 Frog   473 HQRTLQKKTIAVNGDAEEKM---LEK 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	127/624 (20%)
		MFS	59..>234	CDD:119392	51/179 (28%)
		MFS	<449..633	CDD:119392	34/186 (18%)
slc16a10	XP_012819019.1	MFS_MCT10	75..455	CDD:341022	111/573 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010