Protein Alignment hrm and slc16a7

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001106392.1
• Gene: slc16a7 / 100127205
• XenbaseID: XB-GENE-1008526
• Length: 475
• Species: Xenopus tropicalis
• Alignment Length: 642
• Identity: 144/642 - (22%)
• Similarity: 237/642 - (36%)
• Gaps: 220/642 - (34%)

  Fly    49 PPDGGWGWLVLLGSCLT---NILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGP 110
            ||||||||:|:.||.::   :...|   |:..|.|.|..:.||:|.::.|||.::...:..:.||
 Frog    12 PPDGGWGWVVVFGSFISIGFSYAFP---KAITVFFKEIQEIFNTSYSEIAWISSIMLAVMYAGGP 73

  Fly   111 VSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYF 175
            :||||..||..|.|.:.||...||.||.:.:.:|:..|||..||:.|.|...:..|::.|:..||
 Frog    74 ISSILVNKYGSRPVVIGGGVLCSLAMISASFCNSVMQLYICIGVMGGFGLAFNLQPSLTIIGKYF 138

  Fly   176 AKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVR 240
            .|.|.:||||.::||.:....|.||.::|...:|:.||.||:||:.||..||.....|:.
 Frog   139 FKKRPIANGLAMAGSPVFLSTLAPLNQFLFNQFGWRGSFLILGGLLLNCCVAGSLMRPIG----- 198

  Fly   241 VPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSAS 305
             |:        |.::||          |..||:
 Frog   199 -PK--------PVKKDI----------EKAPKD-------------------------------- 212

  Fly   306 AAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSK 370
                       ||...:...:...:
 Frog   213 -----------DENHKKKESVCQSI---------------------------------------- 226

  Fly   371 SRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDAR 435
                                                                             
 Frog   227 ----------------------------------------------------------------- 226

  Fly   436 GQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNF---IILLPSFGEARGFNKSLSAYLLS 497
                    :|:.||||.|...:|:.|   |.|.|.:..|   |:.|..:.:..|.::..||:|||
 Frog   227 --------NKYLDLSLFKHRGFLIYL---SGNVIMFIGFFAPIVFLAPYAKHMGIDQYSSAFLLS 280

  Fly   498 VVSATDLIGRIGGSALSDMGYI-PKTWYFVG-GLSISGLSLALLPFAWTYSSVCFWCALFGLASG 560
            :::..|::.|.....:::..:| |:..||.. .:..:|:...|.|.|..|:.:..:...||.|.|
 Frog   281 ILAFVDMVARPTMGMVANTRFIRPRIQYFFSFAILYNGVCHLLCPLANDYTGLVIYAVFFGFAFG 345

  Fly   561 IYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAG 625
            :...:....:.|::|..|.:|:.|::..|.....|:||||..:..:...:|..::...|:.::.
 Frog   346 MVSSVLFETLMDIVGAARFSSAVGLTTIVECCPVLIGPPLGGFLVDVTGNYKYMYFVCGVIVII- 409

  Fly   626 ASLWSFM-PWINRR------------------------KANAEEQLDAQIEKAAVDS 657
            ||:|.|: ..||.|                        ..|..|.||...:.:.||:
 Frog   410 ASIWLFIGNAINYRMLAKEKMATSAKNIDEKTDLKETEPLNNPETLDVATKSSKVDA 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	142/636 (22%)
		MFS	59..>234	CDD:119392	64/177 (36%)
		MFS	<449..633	CDD:119392	50/189 (26%)
slc16a7	NP_001106392.1	2A0113	10..447	CDD:273325	138/621 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920