DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC4 and Efcab3

DIOPT Version :9

Sequence 1:	NP_001163055.1	Gene:	TpnC4 / 35498	FlyBaseID:	FBgn0033027	Length:	153	Species:	Drosophila melanogaster
Sequence 2:	XP_017170251.1	Gene:	Efcab3 / 70894	MGIID:	1918144	Length:	1435	Species:	Mus musculus

Alignment Length:	193	Identity:	43/193 - (22%)
Similarity:	83/193 - (43%)	Gaps:	52/193 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DKEQLRILRNAFKAFDHDGAGSI-EHADVSSILEILGQKLEPPAVKALIK----EVDKGTTGKL- 65
            :||:|::|::...:.|    |.| :...::|:.:|.|:|::...:..::|    |::|.....|
Mouse   736 EKEELKLLKSLPVSKD----GKIYKKRLLNSVAQIKGKKVQVSNIPLILKNAEFELEKEDCEDLM 796

  Fly    66 -----------DFSQFCKLAARFIEVEEDVGALQN---------------ELKEAFRVYDKEGKG 104
                       :.|.....|..|...:.|||.|.|               ||:.|..|| ..||.
Mouse   797 QLLHTDENKMVELSVLLDKAKNFTGEKIDVGNLNNVLRKMGLMLSDNVYKELQHALSVY-TGGKI 860

  Fly   105 YLT-----VATLRG----------ILHELDDKLSNQDLDMIIEEIDADGSGTVDFDEFMQVMT 152
            |.|     |..|:|          :|..:..|:..::.:.:|.::..:|:.|||.:|.:.:::
Mouse   861 YKTRLLKCVKDLKGPRIKVKKVESLLENMGIKVKGEEFEELIAQLPPEGNKTVDLNELLDIVS 923

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC4	NP_001163055.1	PTZ00184	1..152	CDD:185504	43/191 (23%)
		EFh	14..75	CDD:238008	13/77 (17%)
		EFh	90..152	CDD:238008	20/76 (26%)
Efcab3	XP_017170251.1	PTZ00183	<1006..1119	CDD:185503
Efcab3	XP_017170251.1	EF-hand_8	1065..1115	CDD:372744
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833853
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930