DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC4 and CABP4

DIOPT Version :9

Sequence 1:	NP_001163055.1	Gene:	TpnC4 / 35498	FlyBaseID:	FBgn0033027	Length:	153	Species:	Drosophila melanogaster
Sequence 2:	XP_011543483.1	Gene:	CABP4 / 57010	HGNCID:	1386	Length:	295	Species:	Homo sapiens

Alignment Length:	152	Identity:	50/152 - (32%)
Similarity:	82/152 - (53%)	Gaps:	3/152 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DGEYDKEQLRILRNAFKAFDHDGAGSIEHADVSSILEILGQKLEPPAVKALIKEVDKGTTGKLDF 67
            |.|...|:|..|:.||:.||.|..|.|.|.::...:..||.......:..:.:.:.....|::||
Human   143 DRELGPEELDELQAAFEEFDTDRDGYISHRELGDCMRTLGYMPTEMELLEVSQHIKMRMGGRVDF 207

  Fly    68 SQFCKLAARFIEVEEDVGAL-QNELKEAFRVYDKEGKGYLTVATLR-GILHELDDKLSNQDLDMI 130
            .:|.:|....:. ||....| ..||:.|||.:|::..|.:|||.|| .:...|.:.|:..:||.:
Human   208 EEFVELIGPKLR-EETAHMLGVRELRIAFREFDRDRDGRITVAELREAVPALLGEPLAGPELDEM 271

  Fly   131 IEEIDADGSGTVDFDEFMQVMT 152
            :.|:|.:|.||||||||:.:::
Human   272 LREVDLNGDGTVDFDEFVMMLS 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC4	NP_001163055.1	PTZ00184	1..152	CDD:185504	50/150 (33%)
		EFh	14..75	CDD:238008	16/60 (27%)
		EFh	90..152	CDD:238008	27/62 (44%)
CABP4	XP_011543483.1	PHA03415	81..>190	CDD:177643	15/46 (33%)
		PTZ00184	145..294	CDD:185504	49/150 (33%)
		EFh	153..214	CDD:238008	15/60 (25%)
		EFh	230..293	CDD:238008	27/62 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143672
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930