DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC4 and MYL4

DIOPT Version :9

Sequence 1:	NP_001163055.1	Gene:	TpnC4 / 35498	FlyBaseID:	FBgn0033027	Length:	153	Species:	Drosophila melanogaster
Sequence 2:	XP_011523141.2	Gene:	MYL4 / 4635	HGNCID:	7585	Length:	228	Species:	Homo sapiens

Alignment Length:	181	Identity:	40/181 - (22%)
Similarity:	76/181 - (41%)	Gaps:	36/181 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DGEYDKEQLRI----------------------LRNAFKAFDHDGAG--SIEHADVSSILEILGQ 43
            :|||.:..|.:                      .:.||..||....|  .|.:.....:|..|||
Human    54 EGEYGQPHLSVSIALSWRRRRRRKKRRSSCPHEFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQ 118

  Fly    44 KLEPPAVKALIKEVDKG-----TTGKLDFSQFCKLAARFIEVEEDVGALQNELKEAFRVYDKEGK 103
            .   |....:::.:.|.     ....|||..|..: .:.|...::.|..: :..|..||:|||..
Human   119 N---PTNAEVLRVLGKPKPEEMNVKMLDFETFLPI-LQHISRNKEQGTYE-DFVEGLRVFDKESN 178

  Fly   104 GYLTVATLRGILHELDDKLSNQDLDMIIEEIDADGSGTVDFDEFMQ-VMTG 153
            |.:..|.||.:|..|.:|::..:::.::.. ..|.:|.::::.|:: :|:|
Human   179 GTVMGAELRHVLATLGEKMTEAEVEQLLAG-QEDANGCINYEAFVKHIMSG 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC4	NP_001163055.1	PTZ00184	1..152	CDD:185504	38/178 (21%)
		EFh	14..75	CDD:238008	16/67 (24%)
		EFh	90..152	CDD:238008	16/62 (26%)
MYL4	XP_011523141.2	EFh_PEF	86..227	CDD:330173	34/146 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1470794at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010