DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC4 and MYL3

DIOPT Version :9

Sequence 1:	NP_001163055.1	Gene:	TpnC4 / 35498	FlyBaseID:	FBgn0033027	Length:	153	Species:	Drosophila melanogaster
Sequence 2:	NP_000249.1	Gene:	MYL3 / 4634	HGNCID:	7584	Length:	195	Species:	Homo sapiens

Alignment Length:	152	Identity:	38/152 - (25%)
Similarity:	71/152 - (46%)	Gaps:	13/152 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EYDKEQLRILRNAFKAFDHDG--AGSIEHADVSSILEILGQKLEPPAVKALIKEVDKG-----TT 62
            |:..||:...:.||..||...  ...|.:.....:|..|||.   |....:::.:.|.     .|
Human    45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQN---PTQAEVLRVLGKPRQEELNT 106

  Fly    63 GKLDFSQFCKLAARFIEVEEDVGALQNELKEAFRVYDKEGKGYLTVATLRGILHELDDKLSNQDL 127
            ..:||..|..: .:.|...:|.|..: :..|..||:||||.|.:..|.||.:|..|.::|:..::
Human   107 KMMDFETFLPM-LQHISKNKDTGTYE-DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEV 169

  Fly   128 DMIIEEIDADGSGTVDFDEFMQ 149
            :.::.. ..|.:|.::::.|::
Human   170 EKLMAG-QEDSNGCINYEAFVK 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC4	NP_001163055.1	PTZ00184	1..152	CDD:185504	38/152 (25%)
		EFh	14..75	CDD:238008	15/67 (22%)
		EFh	90..152	CDD:238008	17/60 (28%)
MYL3	NP_000249.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
MYL3	NP_000249.1	PTZ00184	44..194	CDD:185504	38/152 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1470794at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010