DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC4 and MYL1

DIOPT Version :9

Sequence 1:	NP_001163055.1	Gene:	TpnC4 / 35498	FlyBaseID:	FBgn0033027	Length:	153	Species:	Drosophila melanogaster
Sequence 2:	NP_524144.1	Gene:	MYL1 / 4632	HGNCID:	7582	Length:	194	Species:	Homo sapiens

Alignment Length:	151	Identity:	38/151 - (25%)
Similarity:	71/151 - (47%)	Gaps:	13/151 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EYDKEQLRILRNAFKAFDHDGAGSIEHADVSSILEILGQKLEPPAVKALIKEV------DKGTTG 63
            |:.|||....:.||..||..|...|..:.|..:|..||..    ...|.:::|      ::....
Human    46 EFSKEQQDEFKEAFLLFDRTGDSKITLSQVGDVLRALGTN----PTNAEVRKVLGNPSNEELNAK 106

  Fly    64 KLDFSQFCKLAARFIEVEEDVGALQNELKEAFRVYDKEGKGYLTVATLRGILHELDDKLSNQDLD 128
            |::|.||..:.......::.  |...:..|..||:||||.|.:..|.||.:|..|.:|:..::::
Human   107 KIEFEQFLPMMQAISNNKDQ--ATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVE 169

  Fly   129 MIIEEIDADGSGTVDFDEFMQ 149
            .::.. ..|.:|.::::.|::
Human   170 ALMAG-QEDSNGCINYEAFVK 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC4	NP_001163055.1	PTZ00184	1..152	CDD:185504	38/151 (25%)
		EFh	14..75	CDD:238008	16/66 (24%)
		EFh	90..152	CDD:238008	17/60 (28%)
MYL1	NP_524144.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35
		PTZ00184	45..193	CDD:185504	38/151 (25%)
		EFh	54..118	CDD:298682	16/67 (24%)
		EF-hand_6	54..83	CDD:290141	8/28 (29%)
		EFh	131..192	CDD:238008	17/60 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1470794at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010