DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TpnC4 and Myl3

DIOPT Version :9

Sequence 1:	NP_001163055.1	Gene:	TpnC4 / 35498	FlyBaseID:	FBgn0033027	Length:	153	Species:	Drosophila melanogaster
Sequence 2:	NP_001351413.1	Gene:	Myl3 / 17897	MGIID:	97268	Length:	204	Species:	Mus musculus

Alignment Length:	149	Identity:	39/149 - (26%)
Similarity:	72/149 - (48%)	Gaps:	7/149 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EYDKEQLRILRNAFKAFDHDGAG--SIEHADVSSILEILGQK-LEPPAVKALIKEVDKGTTGK-L 65
            |:..||:...:.||..||....|  .|.:.....:|..|||. .:...::.|.|...:....| :
Mouse    54 EFTPEQIEEFKEAFLLFDRTPKGEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNSKMM 118

  Fly    66 DFSQFCKLAARFIEVEEDVGALQNELKEAFRVYDKEGKGYLTVATLRGILHELDDKLSNQDLDMI 130
            ||..|..: .:.|...:|.|..: :..|..||:||||.|.:..|.||.:|..|.::|:..:::.:
Mouse   119 DFETFLPM-LQHISKNKDTGTYE-DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKL 181

  Fly   131 IEEIDADGSGTVDFDEFMQ 149
            :.. ..|.:|.::::.|::
Mouse   182 MAG-QEDSNGCINYEAFVK 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC4	NP_001163055.1	PTZ00184	1..152	CDD:185504	39/149 (26%)
		EFh	14..75	CDD:238008	16/64 (25%)
		EFh	90..152	CDD:238008	17/60 (28%)
Myl3	NP_001351413.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..47
Myl3	NP_001351413.1	EFh_PEF	53..203	CDD:330173	39/149 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1470794at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010