Protein Alignment CG30440 and LOC5667805

DIOPT Version :10

• Sequence 1: NP_610172.1
• Gene: CG30440 / 35496
• FlyBaseID: FBgn0050440
• Length: 1057
• Species: Drosophila melanogaster
• Sequence 2: XP_061512102.1
• Gene: LOC5667805 / 5667805
• VectorBaseID: AGAMI1_004950
• Length: 1099
• Species: Anopheles gambiae
• Alignment Length: 811
• Identity: 183/811 - (22%)
• Similarity: 293/811 - (36%)
• Gaps: 237/811 - (29%)

  Fly   303 VPPSKQ-SKPFHSVDYDYYENIQKLHLSKESERQIRDNGDPNDLQ-NFLKKNLIKATTNEL---L 362
            ||.|.| |....|.|.....:...|..|..::....||.|..|:| ..:.::.|.|.|.|.   |
Mosquito   115 VPLSAQKSSSNQSADCSAAASSLSLSSSMATDDNNSDNSDDTDVQWAVIGRDKISADTAEFSQRL 179

  Fly   363 KAAAQSTKK-----------------CNIDLER-KLNDLNIKEEDHTSNDSGNSYKNDPYLVSMS 409
            .......||                 |: |.|| .|.|:         :|..:::....|| .:|
Mosquito   180 STEEAGMKKTPGTPTVDREDSGRWSICS-DFERDSLPDV---------DDVCDTWNEFIYL-RLS 233

  Fly   410 KINSCKFIRSYNRDCETIFPTGDHSDLNEFRKSFMPQSVDLLSSASVSLSSCDGSCLNKDSICGS 474
            :.|: |.:.||:.|.|          :..|.:.:.|      :.||.::.|
Mosquito   234 EENA-KHLNSYSPDFE----------VTPFDEYYQP------AEASNTIIS-------------- 267

  Fly   475 EEDCCECNEYQCIATPPNELSKDCLNAVEEGVFCNTEYDDFHENLTSSCCCSGSFCDDDGCSYLD 539
                        :...|.||.: .|:..:.....|.:.||.               |||..|:..
Mosquito   268 ------------LRFTPYELHR-ILHGYDLIDLSNDDEDDH---------------DDDVQSHTS 304

  Fly   540 EGLSVDIKSKNVQSLHESGTDEKLSRKTILLARTEDTNDVTQGIS--DGTTYFTGSLNITHLPKS 602
            .. |.|..|..|.:..:..||.::         |...:.:.:|::  |..   ..|....|||..
Mosquito   305 HS-STDSDSVFVDAFVQHPTDVRI---------TPSVDSLDEGVAFRDSP---VESPEPHHLPND 356

  Fly   603 NEIFKKPQDPEMQRHRRGHILKELFETEKIYVNEIASILKGYYDRLKSDESAPASLQGKANVLFG 667
            .:|            :...:::||.:||:.|:|.:...:..|.|.:.:|:: |..|.||...|||
Mosquito   357 IDI------------KISFLIEELLDTERNYINTLEKGIATYIDAVFTDQT-PPELCGKKYHLFG 408

  Fly   668 NLNEIYSFHNDVFLKDLENCISVTERVALCFVK--RRDKF--YQLYSFYCQNIQRSEKLRETLVD 728
            ||..||.||.:.||..|....:..|.:|..||.  ..|.|  |.|||.|....||       |.:
Mosquito   409 NLQYIYRFHRNAFLPRLLTAGNDVELIADAFVHFLDNDSFYGYVLYSMYHPKSQR-------LCE 466

  Fly   729 THM-FFKECQIGLGHKLPLGAYLLKPVQRITKYQLLLKDL---LLFTDNDSCRNELKNALDCMLI 789
            .|: ||::.|...|.||.:.:.:|:|:||:.:|||||..|   |:.......||...:.:
Mosquito   467 QHIEFFRQHQQQHGDKLGVKSLILQPIQRLPRYQLLLTSLFKQLVKKPGAISRNTQLHKV----- 526

  Fly   790 VLKCVNDSMHQISITGFSGDLAKQGELLMQDSFQVWIESKKDIRLRM-----KP-----KRRH-- 842
               ||.:...| ::.|...:.....::|.       .|..:|..:.:     ||     .:.|
Mosquito   527 ---CVAEKRLQ-TLIGIMNESVTVNDILQ-------CEKAEDDEVELGFGVPKPAIVLRNQNHDN 580

  Fly   843 --IFLYQKSLLLCKQTSKSGYNK-----SSYQFKS--DVKMSQIGLTESVSGDAKRFEVWLKGRQ 898
              :|||.      |......:||     ...:|:|  .|.::.:.|.....|....||     |.
Mosquito   581 QVLFLYP------KDNEHVDHNKPINILHQGKFRSVFPVFINDLRLKRQYQGRLFVFE-----RC 634

  Fly   899 EVYTLQASTIGVKEMWV------AEIKRVLFN-QLEKLKGDQIARYNIRHQSLWQKSSCEAPNIT 956
            .:||.|   :.:|.:..      .|::....| |:.||...:..|..|.     .|.:.::|..|
Mosquito   635 VIYTEQ---LDLKSLTYRGHYTHQEVEFDFTNRQILKLSSRRHERLEIE-----VKVNIQSPGKT 691

  Fly   957 HC--------------SLRRTECFE-------LPLND--SNRNTNIRSE-KTCLSDQ---NIVNG 994
            |.              ..|.:..|:       ..|.|  |.||::.||. .:..||.   ::.:.
Mosquito   692 HLPDVMMAIKTIIDRRDQRESFAFDGAAGEALAMLRDTFSRRNSSFRSSFSSTTSDSSFLSVFSS 756

  Fly   995 PSV-----QDQ------HEKNSWSSDCSDID 1014
            |:.     :|.      |...|..|:|..|:
Mosquito   757 PAAAAAAEEDSTAAGSAHRAGSVLSECGSIE 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30440	NP_610172.1	RhoGEF	622..796	CDD:214619	61/181 (34%)
		PH-like	802..925	CDD:473070	27/150 (18%)
LOC5667805	XP_061512102.1	None