Protein Alignment CG30440 and RtGEF

DIOPT Version :9

• Sequence 1: NP_610172.1
• Gene: CG30440 / 35496
• FlyBaseID: FBgn0050440
• Length: 1057
• Species: Drosophila melanogaster
• Sequence 2: NP_001097184.2
• Gene: RtGEF / 35306
• FlyBaseID: FBgn0015803
• Length: 1310
• Species: Drosophila melanogaster
• Alignment Length: 593
• Identity: 112/593 - (18%)
• Similarity: 203/593 - (34%)
• Gaps: 179/593 - (30%)

  Fly   538 LDEGLSVDIKSKNVQSLHESGTDEKLSRK--TILLARTEDTNDVTQGISDGTTYFTGS-LN--IT 597
            :|:.|.|..:    .|...|..||...:|  .|.:.:.||.......::|.|.:|..: :|  ..
  Fly     1 MDQPLVVQAE----YSFMGSNNDELCFQKGDVITVTQREDGGWWEGTLNDKTGWFPSNYVNECKV 61

  Fly   598 HLPKSNEIFKKPQDPEMQRHRRGHILKELFETEKIYVNEIASILKGYYDR------LKSDESAPA 656
            .||.:..|    :.||..:..|..:||:|.::|:.:|.|:..:|:.:.:.      |..||.|.
  Fly    62 QLPLTETI----RPPEEIQEYRSVVLKDLLDSERAHVAELQGLLENFLEPMQQTQILSQDEYAQ- 121

  Fly   657 SLQGKANVLFGNLNEIYSFHNDVFLKDLENCISVTERVALCFVKRRDKFYQLYSFYCQNIQRSEK 721
                    |..|..||...|.|:.:: :|.|   .:||...|:.......:::..||....::..
  Fly   122 --------LMCNFVEIVRTHEDLLIQ-IEEC---NDRVGKLFLTSAPLMKKVHQAYCAAHPKAIV 174

  Fly   722 LRETLVDTHMFFKECQ----IGLGHKLPLGAYLLKPVQRITKYQLLLKDL--------------- 767
            :.:...|....:.|.|    .||   |.|...|.||.:|:.||..:|::|
  Fly   175 ILDKYKDELEKYMERQGAATPGL---LVLTTGLSKPFRRLDKYSAMLQELERHMESSHPDRGDTQ 236

  Fly   768 ---LLFTDNDSCRNELKNALDCMLIVLKCVNDSMHQISITGFSG-DLAKQGELLMQDSFQVWIES 828
               .::.|..:..:..:...:..|.||..        .:.|:.| :|:..|:::...|..|..:.
  Fly   237 RSVAVYKDIAATCSATRRQKELELQVLTG--------PVRGWQGQELSTLGDIIHMGSVAVGADH 293

  Fly   829 KKDIRLRMKPKRRHIFLYQKSLLLCKQTSKSGYNKSSYQFKSDVKMSQIGLTESVSGDAKRFEVW 893
            :.          |:..|:.::||....:.:    .|::.::..:.::.|.:......||
  Fly   294 RD----------RYFVLFPQTLLFLSVSQR----MSAFIYEGKLPLTGIIVNRLEDTDA------ 338

  Fly   894 LKGRQEVYT-----LQASTIGVKE--MWV-----------AEIKRVLFNQLEKLKGDQIARYNIR 940
            ||...|:.:     :.|...|..|  .||           ..|||    ||..|....:...|..
  Fly   339 LKNAFEISSPLIDRIVAVCQGPNEANKWVELLNANNPSLPMGIKR----QLSNLSNSSLGHLNAA 399

  Fly   941 H--QSLWQKSSC------------------------------EAP-------------------- 953
            |  |.|..:..|                              .||
  Fly   400 HLSQHLDSRGYCTRFSLCAYYSSPPCHVRPLRVTLPPSNYPATAPYANLSAHFARLVKGGGLRSA 464

  Fly   954 --------------NITHCSLRRTECFELPLNDSNRNTNIRSEKTCLSDQNIVNGPSVQDQHEKN 1004
                          ::...:||:..|.:......:.|||..|.::.|..|:.:..|:     :..
  Fly   465 IVKMLLYPQARQSIDLKRIALRKRRCHKASAKLKDLNTNQDSGQSELERQDAIELPT-----DSE 524

  Fly  1005 SWSSDCSD 1012
            |:..|..|
  Fly   525 SYDDDFED 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30440	NP_610172.1	RhoGEF	622..796	CDD:214619	43/201 (21%)
		PH-like	802..925	CDD:302622	25/141 (18%)
		PH	829..922	CDD:278594	19/110 (17%)
RtGEF	NP_001097184.2	SH3_PIX	6..58	CDD:212810	12/55 (22%)
		RhoGEF	79..249	CDD:238091	41/185 (22%)
		PH_Cool_Pix	281..376	CDD:269932	18/114 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462272
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840