DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment stw and sks3

DIOPT Version :9

Sequence 1:	NP_001137606.1	Gene:	stw / 35494	FlyBaseID:	FBgn0286203	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_199656.2	Gene:	sks3 / 834900	AraportID:	AT5G48450	Length:	621	Species:	Arabidopsis thaliana

Alignment Length:	557	Identity:	134/557 - (24%)
Similarity:	218/557 - (39%)	Gaps:	108/557 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 GVERGILTANRMIPGPSIQVCENDKVVIDVENHMEGMEVTIHWHGIWQRGSQYYDGVPFVTQCPI 295
            |..:.::..|...|||.:.|..|..||::|:|::: ..:.:.|:||..|.:.:.||| ..|.|||
plant    44 GTRQQVIGINGQFPGPILNVTTNWNVVMNVKNNLD-EPLLLTWNGIQHRKNSWQDGV-LGTNCPI 106

  Fly   296 QQG-N-TFRYQWTGNAGTHFWHAHTGLQKLDGLYGSVVVRQPPSRDPNSHLYDFDLTTHIMLISD 358
            ..| | |:.:|.....|:.|:...|..|:..|.||.::|...........|.|.|:|   :.|||
plant   107 PSGWNWTYEFQVKDQIGSFFYFPSTNFQRASGGYGGIIVNNRAIIPVPFALPDGDVT---LFISD 168

  Fly   359 W-------LHEDAAERYPGRLAVNTGQDPESMLINGKGQFRDPNTGFMTNTPLEIFTITPGRRYR 416
            |       |.:|...:       |..:.|:.::|||.|.|..      ..:|.....:.|||.||
plant   169 WYTKSHKKLRKDVESK-------NGLRPPDGIVINGFGPFAS------NGSPFGTINVEPGRTYR 220

  Fly   417 FRMINAFASVCPAQVTIEGHGMTVIATDGEPVHPVDVNTIISFSGERYDFVISADQPVGA--YWI 479
            ||:.|: .........|:.|.:.::.|:|......:...:....|:.:.|:::.||. |:  |:|
plant   221 FRVHNS-GIATSLNFRIQNHNLLLVETEGSYTIQQNYTNMDIHVGQSFSFLVTMDQS-GSNDYYI 283

  Fly   480 QLRGLGECGIRRAQQLAILRYARGPYQPASSPPTYDVGIPQGVILNPLDAICDRKRADAVCVSNL 544
            .........| :|..:|:|||:.. ..|||.|      :|...|  .||......:|.::.::..
plant   284 VASPRFATSI-KASGVAVLRYSNS-QGPASGP------LPDPPI--ELDTFFSMNQARSLRLNLS 338

  Fly   545 KNAKK--------------VDKGVLVERPDVKIFLPFRFFVYEPKALFIPNTYNRFLVVPSGDHL 595
            ..|.:              .|..|:|.||...|                            ...|
plant   339 SGAARPNPQGSFKYGQITVTDVYVIVNRPPEMI----------------------------EGRL 375

  Fly   596 TSLVDEISYISPPAPP--LSQIDDIPPEYFCNGDNRPPNCGPNCECTHMVDIPLGAIVEVVLVDE 658
            .:.::.|||: |||.|  |:|..:|...|..:...||.|..|..: |.:::......||::..:.
plant   376 RATLNGISYL-PPATPLKLAQQYNISGVYKLDFPKRPMNRHPRVD-TSVINGTFKGFVEIIFQNS 438

  Fly   659 VQQVNLSHPFHLHGTAFYVVGL--GRSPDKSIKKINLKHALELDQMGMLERHFSKPPLKDTIAVP 721
            ...|.   .:||.|.||:|||:  |...:.|....|...|:                .:.|..|.
plant   439 DTTVK---SYHLDGYAFFVVGMDFGLWTENSRSTYNKGDAV----------------ARSTTQVF 484

  Fly   722 NNGYVVIRFRADNPGYWLFHCHFLFHIVIGMNLIFHI 758
            ...:..:....||.|.|......|....:|..|...:
plant   485 PGAWTAVLVSLDNAGMWNLRIDNLASWYLGQELYLSV 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stw	NP_001137606.1	ascorbase	230..756	CDD:274555	134/553 (24%)
		CuRO_1_tcLCC2_insect_like	230..333	CDD:259927	33/103 (32%)
		CuRO_2_tcLCC_insect_like	352..500	CDD:259951	37/156 (24%)
		CuRO_3_tcLLC2_insect_like	599..767	CDD:259972	40/164 (24%)
sks3	NP_199656.2	PLN00044	17..559	CDD:165622	134/557 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2132
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454773at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11709
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880