DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment stw and LAC14

DIOPT Version :9

Sequence 1:	NP_001137606.1	Gene:	stw / 35494	FlyBaseID:	FBgn0286203	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_196498.1	Gene:	LAC14 / 830795	AraportID:	AT5G09360	Length:	569	Species:	Arabidopsis thaliana

Alignment Length:	587	Identity:	159/587 - (27%)
Similarity:	248/587 - (42%)	Gaps:	121/587 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 ILTANRMIPGPSIQVCENDKVVIDVENHMEGMEVTIHWHGIWQRGSQYYDGVPFVTQCPIQQGNT 300
            |||.|...|||:::....||::::|.|: ....:|:||||..|..:.:.||..:||||||:.|.:
plant    56 ILTVNGEFPGPTLKAYRGDKLIVNVINN-ANYNITLHWHGARQIRNPWSDGPEYVTQCPIRPGES 119

  Fly   301 FRYQ--WTGNAGTHFWHAHTGLQKLDGLYGSVVVRQPPSRDPNSHLYDFDLTTH---IMLISDWL 360
            :.|:  .....||.:||||:...:.. ::|:.:|.  |.|..:   |.|. ..|   .:::.:|.
plant   120 YVYRIDLKVEEGTIWWHAHSQWARAT-VHGAFIVY--PKRGSS---YPFP-KPHREIPLILGEWW 177

  Fly   361 HEDAAERYPGRLAVNTGQDP---ESMLINGKGQFRDPNTGFMTNTPLEIF--TITPGRRYRFRMI 420
            .::.....||: |..||.:|   :|..|||:     |...:..:.| |.|  |:..||||..|:|
plant   178 KKENIMHIPGK-ANKTGGEPAISDSYTINGQ-----PGYLYPCSKP-ETFKITVVRGRRYLLRII 235

  Fly   421 NA-------FASVCPAQVTIEGHGMTVIATDGEPVHPVDVNTIISFSGERYDFVISADQPVGAYW 478
            ||       ||        |..|.:||:|.||..:.....:.::...|:..|.::.|:|....|:
plant   236 NAVMDEELFFA--------IANHTLTVVAKDGFYLKHFKSDYLMITPGQSMDVLLHANQRPNHYF 292

  Fly   479 IQLRGLGE---CGIRRAQQLAILRYARGPYQPASSPPTYDVGIPQGVILNPLDAIC------DRK 534
            :..|....   .|..:....|||:|                   :|..||.:..|.      :|.
plant   293 VAARAYSSAFGAGFDKTTTTAILQY-------------------KGDTLNRIKPILPYLPPYNRT 338

  Fly   535 RADAVCVSNLKNAKKVDKGVLVERPDVKIFLPFRFFVYEPKALFIPNTYNRFLVVPSGDHLTSLV 599
            .|.....:..::.:.|:..|.:...          .:|......:..:.:|....|.|...:|.:
plant   339 EASTRFTNQFRSQRPVNVPVKINTR----------LLYAISVNLMNCSDDRPCTGPFGKRFSSSI 393

  Fly   600 DEISYISPPAPPLSQI---------DDI---PPEYF-CNGDNRPPNCGPNCECTHMVDIPLGAIV 651
            :.||:::|....|...         :|.   ||..| ..|:|.|   .|....|.:|.:...:.|
plant   394 NNISFVNPSVDILRAYYRHIGGVFQEDFPRNPPTKFNYTGENLP---FPTRFGTKVVVLDYNSSV 455

  Fly   652 EVVLVDEVQQVNLSHPFHLHGTAFYVVGLG-----RSPDKSIKKINLKHALELDQMGMLERHFSK 711
            |::|.......:..||.||||..|||||.|     |..|.                  |..:...
plant   456 ELILQGTTVWASNIHPIHLHGYNFYVVGSGFGNFDRRKDP------------------LRYNLVD 502

  Fly   712 PPLKDTIAVPNNGYVVIRFRADNPGYWLFHCHFLFHIVIGMNLIFHI--GTTADLPPV--PPRFP 772
            ||.:.|:.||.||:..:||.|:|||.||.|||...|...|||.:|.:  |.|.....|  ||..|
plant   503 PPEETTVGVPRNGWTAVRFVANNPGVWLLHCHIERHATWGMNTVFIVKDGPTKSSRMVKPPPDLP 567

  Fly   773 TC 774
            :|
plant   568 SC 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stw	NP_001137606.1	ascorbase	230..756	CDD:274555	151/563 (27%)
		CuRO_1_tcLCC2_insect_like	230..333	CDD:259927	34/98 (35%)
		CuRO_2_tcLCC_insect_like	352..500	CDD:259951	44/165 (27%)
		CuRO_3_tcLLC2_insect_like	599..767	CDD:259972	57/187 (30%)
LAC14	NP_196498.1	laccase	33..569	CDD:274556	158/585 (27%)
		CuRO_1_LCC_plant	38..154	CDD:259918	35/101 (35%)
		CuRO_2_LCC_plant	169..317	CDD:259943	43/162 (27%)
		CuRO_3_LCC_plant	416..552	CDD:259964	51/156 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	85	1.000	Domainoid score	I2814
eggNOG	1	0.900	-	-		E1_COG2132
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58299
OrthoDB	1	1.010	-	-		D454773at2759
OrthoFinder	1	1.000	-	-		FOG0000424
OrthoInspector	1	1.000	-	-		mtm1062
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11709
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X253
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.890