DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment stw and SKS1

DIOPT Version :9

Sequence 1:	NP_001137606.1	Gene:	stw / 35494	FlyBaseID:	FBgn0286203	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_001320060.1	Gene:	SKS1 / 828627	AraportID:	AT4G25240	Length:	589	Species:	Arabidopsis thaliana

Alignment Length:	567	Identity:	138/567 - (24%)
Similarity:	228/567 - (40%)	Gaps:	97/567 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 GVERGILTANRMIPGPSIQVCENDKVVIDVENHMEGMEVTIHWHGIWQRGSQYYDGVPFVTQCPI 295
            ||.:.::..|...|||.:....|..||::|.||:: ..:.:.|.||..|.:.:.||| ..|.|||
plant    44 GVPQQVIAVNGQFPGPLLNATTNYNVVVNVFNHLD-EPLLLTWPGIQMRRNSWQDGV-LGTNCPI 106

  Fly   296 --QQGNTFRYQWTGNAGTHFWHAHTGLQKLDGLYGSVVVRQP-----PSRDPNSHLYDFDLTTHI 353
              :...|:::|.....|:.|:......|:..|.:|.:|:...     |...|:..|        |
plant   107 PPRWNFTYQFQVKDQIGSFFYSPSLNFQRASGGFGPIVINNRDIIPIPFPQPDGEL--------I 163

  Fly   354 MLISDWLHEDAAERYPGRLAVNTGQD---PESMLINGKGQFRDPNTGFMTNTPLEI----FTITP 411
            .:|.||..:|....   |.|:::|::   |:.:||||||.::     :.::.|..|    |.:.|
plant   164 FIIGDWYTQDHKAL---RRALDSGKELGMPDGVLINGKGPYK-----YNSSVPDGIDYLTFHVEP 220

  Fly   412 GRRYRFRMINAFASVCPAQVTIEGHGMTVIATDGEPVHPVDVNTIISFSGERYDFVISADQPVGA 476
            |:.||.|:.|...|. .....|:.|.:.::.|:|......:........|:.|.|:::.||...:
plant   221 GKTYRIRVHNVGIST-SLNFRIQNHSLLLVETEGHYTSQANFTDFDVHVGQSYSFLVTMDQDATS 284

  Fly   477 -YWI--QLRGLGECGIRRAQQLAILRY--ARGPYQPASSPPTYDVGIPQGVILNPLDAICDRKRA 536
             |:|  ..|.:.|...:|...:|||.|  ::||.......|..||..|...:..|...   |:..
plant   285 DYYIVASARFVNETVWQRVTGVAILHYSNSKGPVSGPLPVPKTDVSSPWSAMSQPKTI---RQNT 346

  Fly   537 DAVCVSNLKNAKKVDKGVLVERPDVKIFLPFRFFVYEPKALFIPNTYNRFLVVPS--GDHLTSLV 599
            .|             .|.   ||:     |...|.|  ..:.|.|||....:.|:  ...|.:.:
plant   347 SA-------------SGA---RPN-----PQGSFHY--GQINITNTYILRSLPPTIINGALRATL 388

  Fly   600 DEISYISPPAP-PLSQIDDIPPEYFCNGDNRPPNCGPNCECTHMVDIPLGAIVEVVLVDEVQQVN 663
            :.||:::|..| .|:..:.:...|..:..:||.| .|......|::......::||..:...::
plant   389 NGISFVNPSTPVRLADRNKVKGAYKLDFPDRPFN-RPLRLDRSMINATYKGFIQVVFQNNDTKI- 451

  Fly   664 LSHPFHLHGTAFYVVGLG---RSPDKSIKKINLKHALELDQMGMLERHFSKPPLKDTIAVPNNGY 725
              ..||:.|.:|:|||:.   .|.||. ...|...|:.                :.||.|...|:
plant   452 --QSFHVDGYSFFVVGMDFGIWSEDKK-GSYNNWDAIS----------------RSTIEVYPGGW 497

  Fly   726 VVIRFRADNPGYWLFHCHFLFHIVIGMNLIFHI------GTTADLPP 766
            ..:....||.|.|......|....:|......|      |.|...||
plant   498 TAVLISLDNVGVWNIRVENLDRWYLGEETYMRITNPEEDGKTEMDPP 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stw	NP_001137606.1	ascorbase	230..756	CDD:274555	133/549 (24%)
		CuRO_1_tcLCC2_insect_like	230..333	CDD:259927	31/103 (30%)
		CuRO_2_tcLCC_insect_like	352..500	CDD:259951	42/157 (27%)
		CuRO_3_tcLLC2_insect_like	599..767	CDD:259972	40/178 (22%)
SKS1	NP_001320060.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2132
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454773at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11709
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880