DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment stw and LAC7

DIOPT Version :9

Sequence 1:	NP_001137606.1	Gene:	stw / 35494	FlyBaseID:	FBgn0286203	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_187533.1	Gene:	LAC7 / 820078	AraportID:	AT3G09220	Length:	567	Species:	Arabidopsis thaliana

Alignment Length:	605	Identity:	174/605 - (28%)
Similarity:	255/605 - (42%)	Gaps:	142/605 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 ERGILT-ANRMIPGPSIQVCENDKVVIDVENHMEGMEVTIHWHGIWQRGSQYYDGVPFVTQCPIQ 296
            :|.::| .|..:|||:|:|.|.|.:||.|.|| ....:|||||||:.:.:.:.||...:||||||
plant    42 KRQVITVVNGSLPGPTIRVKEGDSLVIHVLNH-SPHNITIHWHGIFHKLTVWADGPSMITQCPIQ 105

  Fly   297 QGNTFRYQW--TGNAGTHFWHAHTGLQKLDGLYGSVVVRQPPSRDPNSHLYDFDLTTH---IMLI 356
            .|..:.|::  ||..||.:||||....:.. :||::|:| |.|    .|.|.|. ..|   .:|.
plant   106 PGQRYAYRFNITGQEGTLWWHAHASFLRAT-VYGALVIR-PKS----GHSYPFP-KPHKEVPILF 163

  Fly   357 SDWLHED--AAERYPGRLAVNTGQDP---ESMLINGKGQFRDPNTGFMTNTPLEIFTITPGRRYR 416
            .:|.:.|  |.|    ..|:.||..|   ::..|||    |..|....:...:....:..|:||.
plant   164 GEWWNTDVVALE----EAAIATGVPPNNSDAYTING----RPGNLYPCSKDRMFSLNVVKGKRYL 220

  Fly   417 FRMINAFASVCPAQV--TIEGHGMTVIATDGEPVHPVDVNTIISFSGERYDFVISADQPVG-AYW 478
            .|:|||..::   |:  .|..|.:||:|.|.....|...:.|:...|:..|.::.|||.|. :|:
plant   221 LRIINAAMNI---QLFFKIANHRLTVVAADAVYTAPYVTDVIVIAPGQTIDALLFADQSVDTSYY 282

  Fly   479 IQLRGLGECGIRRAQQLAILRYARGPYQPASSPPTYDVGIPQGVILNPLDAICDRKRADAVCVSN 543
                            :|...||..|..|..:..|      :|||                   :
plant   283 ----------------MAAHPYASAPAVPFPNTTT------RGVI-------------------H 306

  Fly   544 LKNAKKVDKGVLVERPDVKIFL----PFRFF------VYEPKALFIPNTYNRFLVVPSGDHLTSL 598
            ...|.|..:...|..|.:..|.    .:||:      |..|..:.:|...:..::|..|..|.:.
plant   307 YGGASKTGRSKPVLMPKLPSFFDTLTAYRFYSNLTALVNGPHWVPVPRYVDEEMLVTIGLGLEAC 371

  Fly   599 VDEI------------SYISPPAPPL-------------SQIDDIPPEYFCNGDNRPPN---CGP 635
            .|..            |::.|....:             :...|.||..|   |...||   ..|
plant   372 ADNTTCPKFSASMSNHSFVLPKKLSILEAVFHDVKGIFTADFPDQPPVKF---DYTNPNVTQTNP 433

  Fly   636 NC----ECTHMVDIPLGAIVEVVLVDEVQQVNLSHPFHLHGTAFYVV--GLGR-SPDKSIKKINL 693
            ..    :.|....:.....|||||.:.......|||.||||..|:|:  |.|. .|.:...|:||
plant   434 GLLFTQKSTSAKILKFNTTVEVVLQNHALIAAESHPMHLHGFNFHVLAQGFGNYDPSRDRSKLNL 498

  Fly   694 KHALELDQMGMLERHFSKPPLKDTIAVPNNGYVVIRFRADNPGYWLFHCHFLFHIVIGMNLIFHI 758
                 :|           |..::|:|||..|:.||||.|:|||.|:||||...|:..|:.:||.:
plant   499 -----VD-----------PQSRNTLAVPVGGWAVIRFTANNPGAWIFHCHIDVHLPFGLGMIFVV 547

  Fly   759 --GTT--ADLPPVPPRFPTC 774
              |.|  ..|||.||..|.|
plant   548 KNGPTKSTTLPPPPPDLPKC 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stw	NP_001137606.1	ascorbase	230..756	CDD:274555	163/581 (28%)
		CuRO_1_tcLCC2_insect_like	230..333	CDD:259927	43/102 (42%)
		CuRO_2_tcLCC_insect_like	352..500	CDD:259951	39/158 (25%)
		CuRO_3_tcLLC2_insect_like	599..767	CDD:259972	60/206 (29%)
LAC7	NP_187533.1	laccase	23..550	CDD:274556	165/586 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	85	1.000	Domainoid score	I2814
eggNOG	1	0.900	-	-		E1_COG2132
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58299
OrthoDB	1	1.010	-	-		D454773at2759
OrthoFinder	1	1.000	-	-		FOG0000424
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11709
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X253
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.890