Protein Alignment stw and Hephl1

DIOPT Version :10

• Sequence 1: NP_610170.2
• Gene: stw / 35494
• FlyBaseID: FBgn0286203
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001178922.2
• Gene: Hephl1 / 500946
• RGDID: 1564835
• Length: 1159
• Species: Rattus norvegicus
• Alignment Length: 882
• Identity: 168/882 - (19%)
• Similarity: 274/882 - (31%)
• Gaps: 319/882 - (36%)

  Fly    33 VANSQQN--QPKKENQP------------DLTPMGSFWQQHVATPSSSTPFDSPFFSATHGLVQT 83
            |.|.:.|  .||...|.            |.:|.|  :.:....|.:::..||..:     ..|.
  Rat   362 VGNCRGNAPHPKMRGQQRRYFIAAEKVLWDYSPQG--YDKFTGFPLNTSGSDSAVY-----FTQA 419

  Fly    84 HPSIGGSH-------SGPAPLNGNSLGSGAPSSI-LAGTKPALTAGSG------YLNSRGS---- 130
            ...|||.:       ...|..:...:.|.:.:.: :.|  |.:.|..|      :.|....
  Rat   420 DNRIGGKYWKARYTEYVDATFSRRKMPSDSEAHLGILG--PVIKAEVGDILLVTFANKADKVYSI 482

  Fly   131 LPTSARYPANKITGTVVEPNPKSPFRHLDFSTSATAELRRNPALSAPDECARACREGEPPRICYY 195
            ||....|......|..|:...| |..|:....:.|.......::|..|:        :||.:.|.
  Rat   483 LPHGVFYDKASDAGPNVDGFLK-PGAHVKPGETFTYRWTVPESVSPTDD--------DPPCLTYL 538

  Fly   196 HFTL-----EYYTVLGAACQVCTPNATNTVWSHCQCVLADGVERGI------------------- 236
            :|:.     :....|.....||.....|          |||.::||
  Rat   539 YFSAVQPIKDTSAGLVGPLLVCKKGTLN----------ADGTQKGIDKEFYLLFTVFDENFSSYL 593

  Fly   237 ---------------------LTANRM--IPG------PSIQVCENDKVVIDVENHMEGMEVTIH 272
                                 :.:|||  |.|      |.:.:|:.|:    |..|:.||.....
  Rat   594 DENIQKFTWHPFSVDKEDKEFVKSNRMHAINGYMYGNQPGLSMCKKDR----VSWHLIGMGTDTD 654

  Fly   273 WHGIWQRGSQYYDGVPFVTQCPIQQGNTFRYQWTGNAGTH------FWHA---------HTGLQK 322
            .||:      |:            ||||...:     |||      |.|.         |:|:.|
  Rat   655 MHGV------YF------------QGNTIHLR-----GTHRDSLALFPHMSTTAFMQPDHSGIFK 696

  Fly   323 L---------DGLYGSVVVRQPPSRDPNSHLYDFDLTTHIMLISDWLHEDAAERYPGRLAVNTGQ 378
            :         .|:.....|....:|||:...|....|.:|          |||......|.|...
  Rat   697 VFCSTLHHFTRGMGQIYEVSSCGNRDPSEPPYGMLRTFYI----------AAEEVEWDYAPNKNW 751

  Fly   379 DPESMLINGKGQFRDPNTGFMTNTPLEIFTITPGRRYRFRMINAFAS-------VCPAQVTIEGH 436
            :.|...::..|: |..:. ||.:|...|     |.:||..:...:.:       ..|.|   |.|
  Rat   752 EFEKQHLDAGGE-RHGDI-FMNHTENWI-----GSQYRKVVYREYTNGEFVEIKARPPQ---EEH 806

  Fly   437 ----GMTVIATDGEPVHPVDVNTIISFSGERYDFVISADQPVGAYWIQLRGLGECGIRRAQQLAI 497
                |..:.|..|:.:       :|.|..:       |.:|   |.|..:|:.:....:...:
  Rat   807 LQLLGPMIHAEVGDSI-------LIIFKNK-------ASRP---YSITAQGVEDSDSGKFLDV-- 852

  Fly   498 LRYARGPYQPASSP---PTYDVGIPQGVVMNPLDAQCNRQRNDAICVSQLKNALEIDRGILAEKP 559
                     |.:.|   .||...:|:.....|.|..|
  Rat   853 ---------PVTKPGEIKTYRWNVPKRSGPGPSDPNC---------------------------- 880

  Fly   560 DVKIFLPFRFFVYRAEDLFQPNTYNRFL---------------VASDADHLISLI------DEVS 603
                 :|   :||.:...|..:||:..:               ..||.|:..:|:      :|..
  Rat   881 -----IP---WVYFSTANFVKDTYSGLMGPLITCREGVLNEKGRRSDVDYEFALLFLVFNENESW 937

  Fly   604 YISPPSPMLSQY-NDIPQEYYCNGDNRPVDCGENCQCTHKIDVPLNAIVEVVLVDEVQQINISHP 667
            |:   ...:.:| |..|:::      |..|..|.....|.|:..:...:..:::.|...
  Rat   938 YL---DDNIKKYLNKDPRDF------RHTDDFEESNRMHAINGKIFGNLPGLIMTEDSM------ 987

  Fly   668 FHLHGTSFYVLGLGRSPDKQIQRMNLKHALELDQRGLLERQYLKPSLKDTV--AVPNNGYAILRF 730
                 |::|:||:|...|        .|.:.......|.:  :..|.::.|  ..|.....|..|
  Rat   988 -----TNWYLLGIGSEVD--------IHTIHYHAESFLFK--IDKSYREDVYDLFPGTFQTIELF 1037

  Fly   731 RADNPGFWLFHCHFQYHIVIGMNLVFQI--GTPNDLP 765
             ||:||.||.|||...||..||...:.:  ...|.:|
  Rat  1038 -ADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIP 1073

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stw	NP_610170.2	ascorbase	230..775	CDD:274555	125/648 (19%)
Hephl1	NP_001178922.2	CuRO_1_ceruloplasmin	26..208	CDD:259884
		CuRO_2_ceruloplasmin	222..362	CDD:259907	168/882 (19%)
		CuRO_3_ceruloplasmin	376..572	CDD:259886	40/223 (18%)
		CuRO_4_ceruloplasmin	575..718	CDD:259908	29/169 (17%)
		Cupredoxin	732..907	CDD:473140	45/258 (17%)
		Cupredoxin	923..1065	CDD:473140	38/172 (22%)