Protein Alignment stw and Mco1

DIOPT Version :10

• Sequence 1: NP_610170.2
• Gene: stw / 35494
• FlyBaseID: FBgn0286203
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_609287.3
• Gene: Mco1 / 34258
• FlyBaseID: FBgn0032116
• Length: 959
• Species: Drosophila melanogaster
• Alignment Length: 711
• Identity: 250/711 - (35%)
• Similarity: 384/711 - (54%)
• Gaps: 103/711 - (14%)

  Fly   162 TSATAELRRNPALSAPD----------ECARACREGEPPRICYYHFTLEYYTVLGAACQVCTPNA 216
            |:...||:.|.|.|..|          .|.|.|:.|..|..|.|.|.:|:|.....||..|..|.
  Fly   217 TARIEELQDNVAESTDDIWTAEWYRNHPCNRDCQVGAEPMTCRYKFVVEWYQTFSKACYDCPRNL 281

  Fly   217 TNTVWSHCQCVLADGVERGILTANRMIPGPSIQVCENDKVVIDVENHMEGMEVTIHWHGIWQRGS 281
            |:....|  ||:.||:||.|...|||:|||:|:|||.|::|:||:||:.|...:|||||:.|:.:
  Fly   282 TDCSRPH--CVMGDGLERSITVVNRMMPGPAIEVCEGDEIVVDVKNHLLGESTSIHWHGLHQKKT 344

  Fly   282 QYYDGVPFVTQCPIQQGNTFRYQWTGN-AGTHFWHAHTGLQKLDGLYGSVVVRQPPSRDPNSHLY 345
            .|.||||.:|||||....||||.:..: :||||||:|||:|:.||::|::::|:|.:.:|:..||
  Fly   345 PYMDGVPHITQCPITPHATFRYSFPADLSGTHFWHSHTGMQRGDGVFGALIIRKPKTAEPHGGLY 409

  Fly   346 DFDLTTHIMLISDWLHEDAAERYPGRLAVNTGQDPESMLINGKGQFRD----------------- 393
            ||||:.|:|::.||:|:..|..:...........|.::|:||||::.:
  Fly   410 DFDLSEHVMIVQDWIHDTGASIFSYHHHSRGDNKPHNLLVNGKGRYYNRIWAEAKQAHRRAEERT 474

  Fly   394 --------------------------PNT------------GFMTNTPLE-----IFTITPGRRY 415
                                      .||            |.:...|||     |:|:..|.||
  Fly   475 TQPVEPLPKSQVDFVQTLPRQARLAKTNTTKLFPVNSRQKRGNLNEIPLELVPHQIYTVRRGFRY 539

  Fly   416 RFRMINAFASVCPAQVTIEGHGMTVIATDGEPVHPVDVNTIISFSGERYDFVISADQPVGAYWIQ 480
            |||:|||....||..|:|:||.:|.|.:||..:..:||.:|:::||||:|||::|:..||.|||:
  Fly   540 RFRIINAEYLNCPIVVSIDGHNLTAINSDGFDIEAMDVGSIVTYSGERFDFVLNANLEVGNYWIR 604

  Fly   481 LRGLGECG--IRRAQQLAILRYARGPYQPASSPPTYDVGI---PQGVVMNPLDAQCNRQRN--DA 538
            |:||.:|.  ...|.|:|||||...|    ...||.::..   .:|:.:|.:    ||...  |.
  Fly   605 LKGLMDCSEVFTSAFQVAILRYEGAP----DEEPTAELSYGHKAEGIELNVM----NRGPGYPDT 661

  Fly   539 ICVSQLK------NALEIDRGILAEKPDVKIFLPFRFFVYRAEDLFQPNTYNRFLVASDADHLIS 597
            ..|::::      :...||...|..:.|.|.|:.:.|:.....|....:.|...:..:..:.|.:
  Fly   662 KTVAEMRALPIYDHVSGIDHDTLKPEADYKFFIYYDFYTKNNPDFHDKDLYAMDMEMTQQNRLYT 726

  Fly   598 -LIDEVSYISPPSPMLSQYNDIPQEYYCNGD---NRPVDC-GENCQCTHKIDVPLNAIVEVVLVD 657
             .::.::...|...:|...:.:....:||..   ::.:|| .|.|:|.|.:.|||.|:||:::||
  Fly   727 PQLNHITLNFPSLALLPSRSQLKDSDFCNETSLMDQGIDCRQEFCKCHHVLQVPLGAVVEMIIVD 791

  Fly   658 EVQQINISHPFHLHGTSFYVLGLGRSPDKQIQRMNLKHALELDQRGLLERQYLKPSLKDTVAVPN 722
            |..|...:|||||||.:|.|:||.|..    :.:.::...:|||..||:|....|.:||||.:|:
  Fly   792 EGFQYYANHPFHLHGNAFRVMGLERLG----ENVTVEMIKQLDQFNLLKRNLDNPPVKDTVTIPD 852

  Fly   723 NGYAILRFRADNPGFWLFHCHFQYHIVIGMNLVFQIGTPNDLPPVPPNFPRCGNHLPPIKT 783
            .||.|:||.|.|||:||||||.::|..|||.|||::|..:.:.|||.|||.||::.|.:::
  Fly   853 GGYTIIRFEASNPGYWLFHCHIEFHAEIGMALVFKVGNDDQMVPVPENFPTCGDYNPDLRS 913

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stw	NP_610170.2	ascorbase	230..775	CDD:274555	222/623 (36%)
Mco1	NP_609287.3	VWC	150..212	CDD:214564
		CuRO_1_tcLCC2_insect_like	293..397	CDD:259927	55/103 (53%)
		CuRO_2_tcLCC_insect_like	415..626	CDD:259951	64/210 (30%)
		CuRO_3_tcLLC2_insect_like	728..897	CDD:259972	67/172 (39%)