DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment stw and f8

DIOPT Version :9

Sequence 1:NP_001137606.1 Gene:stw / 35494 FlyBaseID:FBgn0286203 Length:784 Species:Drosophila melanogaster
Sequence 2:XP_009305924.1 Gene:f8 / 100302404 ZFINID:ZDB-GENE-090629-2 Length:1668 Species:Danio rerio


Alignment Length:434 Identity:82/434 - (18%)
Similarity:141/434 - (32%) Gaps:157/434 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   183 ACREGEPPRICYYHFTLEYYTVLGAACQVCTPNATNTVWSHC----------QCVLADGVER--- 234
            ||:|..    |....|||::..           |..|.|.:.          |...|.||::   
Zfish    12 ACQEYS----CVSAKTLEFFIA-----------AVETKWEYVFTDTADPAANQRKFASGVQKYTK 61

  Fly   235 --------GILTANRMIP------GPSIQVCENDKVVIDVENHMEGMEVTIHWHGI--WQR--GS 281
                    ...|..:..|      ||:|:...||:||:..:| ......:|...||  |::  |:
Zfish    62 AVYTEYTDSTFTTPKSKPPWAGIQGPTIRTVVNDRVVVHFKN-FASQSFSISPIGIPYWKQSEGA 125

  Fly   282 QYYDGVPFVTQC--PIQQGNTFRYQW--TGNAG---------THFWHAHTGLQK--LDGLYGSVV 331
            .|.|...|..:.  .:..|..:||.|  :.|:|         |:.:.:...:.:  ..||.|:::
Zfish   126 GYEDSSSFQERADDSVPPGGYYRYVWDISPNSGPTTSDPDCLTYIYSSQVDIIRDFNSGLIGALL 190

  Fly   332 VRQPP--SRDPNSHLYDFDLTTHIMLIS------DWLHE----------DAAERY---------- 368
            :.:..  :.|....:.:|     |:|:|      .|..|          .:..:|          
Zfish   191 ICKTDALTEDRQRRVPEF-----ILLLSVFDESKSWYQEVGRAEKLKKTSSTNQYHTINGYINST 250

  Fly   369 -PGRLA-----------VNTGQDPESMLINGKG---QFRDPNTGFMTNTPLEIFT--ITPGRRYR 416
             ||...           :..|..||...|..:|   :..|.....:..||:...|  :.|....|
Zfish   251 LPGLSVCEKSPQVSWHLIGLGSSPEIHSIQFEGHTLKVFDHKRVTVEMTPMTFTTALMKPSATGR 315

  Fly   417 FRM-----------INAFASV--CPAQVTI-------------------EGHGMTVIATDGEPVH 449
            |.:           :|||.:|  ||....:                   |.:..:|:...|.|:.
Zfish   316 FLISCRIHSHQTAGMNAFFTVENCPEPAPLPLPDKRNVKHTNDDEEEDDEDNMFSVVFKQGGPIS 380

  Fly   450 PVDVNT---------IISFSGERYDFVI-SADQP---VGAYWIQ 480
            .:..:.         .||.....:|:.. |.|:|   .|:.|.:
Zfish   381 VLRSSAKGRPKVWLHYISAEETDWDYTAQSGDRPASSAGSEWFR 424

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
stwNP_001137606.1 ascorbase 230..756 CDD:274555 70/377 (19%)
CuRO_1_tcLCC2_insect_like 230..333 CDD:259927 30/138 (22%)
CuRO_2_tcLCC_insect_like 352..500 CDD:259951 38/217 (18%)
CuRO_3_tcLLC2_insect_like 599..767 CDD:259972
f8XP_009305924.1 Cupredoxin 25..193 CDD:302766 36/179 (20%)
Cupredoxin 207..336 CDD:302766 24/133 (18%)
Cupredoxin 391..563 CDD:302766 8/34 (24%)
Cupredoxin 577..719 CDD:302766
Cupredoxin 1013..1193 CDD:302766
Cupredoxin 1205..1348 CDD:302766
FA58C 1353..1503 CDD:214572
FA58C 1356..1502 CDD:238014
FA58C 1507..1662 CDD:214572
FA58C 1511..1661 CDD:238014
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D454773at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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