DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10417 and PTC5

DIOPT Version :9

Sequence 1:	NP_610169.1	Gene:	CG10417 / 35492	FlyBaseID:	FBgn0033021	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_014733.1	Gene:	PTC5 / 854257	SGDID:	S000005616	Length:	572	Species:	Saccharomyces cerevisiae

Alignment Length:	419	Identity:	91/419 - (21%)
Similarity:	156/419 - (37%)	Gaps:	102/419 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 SSTSAAAAAAALSADGVA--NSRNPSNVVNPMAGADSNTTTSINDLSTKNAALKDDSVNDQNEGS 267
            ||.|.|...|.||...:.  :..:|..:::      .:|...|.|.||..:.    ::|..:...
Yeast    53 SSHSKALNIALLSGSLLLTYSYYSPKKILS------LDTINGIKDYSTNTSG----NINMPSPNP 107

  Fly   268 NGTDFKHTLVSSSNKK-LFATGSNDMTELNQSSKNEFTNSSTSKEFERNI------NSSQDDEF- 324
            .||:.:.:..|.:::. |....|....:|:...::.|.|..|. .|..::      :..:||..
Yeast   108 KGTETQKSQRSQNDQSVLILNDSKIEAKLHDREESHFVNRGTG-IFRYDVAQLPSNHPIEDDHVE 171

  Fly   325 --------TDDDADYEEN-------DNVKSPDTSSAESSDCT------------ENDDDGDEDGN 362
                    ::|....|::       |....|.||...|.|..            :|......|.|
Yeast   172 QIITIPIESEDGKSIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQVYDQNKTVFHSDPN 236

  Fly   363 EDSDEE------ETDEDQMANDNFCANMIEEPGKD---------SGCTAVVCLLQGRD--LYVAN 410
            :..|..      :.|.| :..::| ..:.::|...         ||..|::.|....:  |.||.
Yeast   237 QLIDSAISKGFLKLDND-LVIESF-RKLFQDPNNTNIANTLPAISGSCALLSLYNSTNSILKVAV 299

  Fly   411 AGDSR---CVISRSGQ--AIEMSIDHKPEDDEEASRIIK---AGGRVTLDGRVNGGLNLSRALGD 467
            .||||   |.:...|.  ...:|.|...::.:|..||.|   ....|..:||:.|.|..|||.||
Yeast   300 TGDSRALICGLDNEGNWTVKSLSTDQTGDNLDEVRRIRKEHPGEPNVIRNGRILGSLQPSRAFGD 364

  Fly   468 HAYKTNVTLPAEEQMISALPDIKKLII--TPED----------------------EFMVLACDGI 508
            :.||..   ..:.:.:|.||::.||..  .|.|                      :|||:..||:
Yeast   365 YRYKIK---EVDGKPLSDLPEVAKLYFRREPRDFKTPPYVTAEPVITSAKIGENTKFMVMGSDGL 426

  Fly   509 WNYMSSEEVVEFVRCRLKDNKKLSTICEE 537
            :..:::||:...|...:..|..|:.:..|
Yeast   427 FELLTNEEIASLVIRWMDKNMNLAPVKAE 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10417	NP_610169.1	PP2Cc	18..>100	CDD:214625
CG10417	NP_610169.1	PP2Cc	<374..564	CDD:238083	51/207 (25%)
PTC5	NP_014733.1	PP2C	182..464	CDD:395385	65/279 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810