DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10417 and PTC1

DIOPT Version :9

Sequence 1:	NP_610169.1	Gene:	CG10417 / 35492	FlyBaseID:	FBgn0033021	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_010278.3	Gene:	PTC1 / 851558	SGDID:	S000002164	Length:	281	Species:	Saccharomyces cerevisiae

Alignment Length:	218	Identity:	68/218 - (31%)
Similarity:	109/218 - (50%)	Gaps:	44/218 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 EEETDEDQMANDNFCANMIEEPGK-----DSGCTAVVCLLQ-----------------GRDLYVA 409
            :|..|...:.||:|.|  |:|...     :|||||.||:|:                 .|.||.|
Yeast    84 DETRDVRDVLNDSFLA--IDEEINTKLVGNSGCTAAVCVLRWELPDSVSDDSMDLAQHQRKLYTA 146

  Fly   410 NAGDSRCVISRSGQAIEMSIDHKPEDDEEASRIIKAGGRVTLDGRVNGGLNLSRALGDHAYKTNV 474
            |.||||.|:.|:|.:|.::.|||..|..|..|:.:|||.: :..||||.|.::|:|||..:
Yeast   147 NVGDSRIVLFRNGNSIRLTYDHKASDTLEMQRVEQAGGLI-MKSRVNGMLAVTRSLGDKFF---- 206

  Fly   475 TLPAEEQMISALPDIKKLIITPEDEFMVLACDGIWNYMSSEEVVEFVRCRLKDNKKLSTICEELF 539
                 :.::...|....:.||.||:|::|||||:|:.:..::..|.::...:.|:....:.....
Yeast   207 -----DSLVVGSPFTTSVEITSEDKFLILACDGLWDVIDDQDACELIKDITEPNEAAKVLVRYAL 266

  Fly   540 DNCLAPNTMGDGTGCDNMTAVIV 562
            :|         || .||:|.::|
Yeast   267 EN---------GT-TDNVTVMVV 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10417	NP_610169.1	PP2Cc	18..>100	CDD:214625
CG10417	NP_610169.1	PP2Cc	<374..564	CDD:238083	66/211 (31%)
PTC1	NP_010278.3	PP2Cc	12..279	CDD:214625	67/216 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810