DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10417 and PTC6

DIOPT Version :9

Sequence 1:	NP_610169.1	Gene:	CG10417 / 35492	FlyBaseID:	FBgn0033021	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_010003.2	Gene:	PTC6 / 850441	SGDID:	S000002133	Length:	442	Species:	Saccharomyces cerevisiae

Alignment Length:	454	Identity:	96/454 - (21%)
Similarity:	145/454 - (31%)	Gaps:	129/454 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 NVVNPMAGADSNTTTSINDLSTK-NAALK-------------DDSVNDQNEGSNGTDFKHTLVSS 279
            :::..:.|...:.|:.||.|..: |.::|             :.||.| ..|..|......|...
Yeast    21 DLLRGLPGYVGHATSRINRLENQDNYSIKMMRSWPNAYGSALNCSVFD-GHGEKGAQLSQLLADK 84

  Fly   280 SNKKL-FATGS---NDMTELNQSSKNEFTNSSTSKE----FERNINSSQDDEFTDDDADYEENDN 336
            ....| |...|   .|:.:|.|.....|...:..|.    ||:..|.            :.:|.|
Yeast    85 LCSSLDFPEPSWDKQDLKKLVQEYARRFPEGNYWKHKLSTFEKFYNK------------FIKNCN 137

  Fly   337 VKSPDTSSAESSDCTENDDDG----DEDGN--------EDSDE-------EETDEDQMANDNFCA 382
            .|.......|........:.|    |:.||        .:.|.       ...|.||      |.
Yeast   138 SKQELLLMKEGDSAILGQNGGRMIFDKMGNIIDKIALLTELDRLRLFYGFARFDLDQ------CC 196

  Fly   383 NMIEEPGKDSGCTAVVCLL-----------QGRD-------------LYVANAGDSRCVI-SRSG 422
            .:    |..:|.||....|           :|:|             |.|...|||:.:: .:.|
Yeast   197 GL----GTAAGSTASSIFLYPYDDPNAPIDEGKDDDSWIISHSGLLKLIVTQVGDSKIILCDQDG 257

  Fly   423 QAIEMSIDHKPEDDEEASRIIKAGGRVTLDG----RVNGGLNLSRALGDHAYKTNVTLPAEEQMI 483
            .|..::..|......|..|:.....|:..|.    |.......:|:.||.|.|        ...|
Yeast   258 IAHALTTTHHINSSRERHRLSIDPSRLDPDAFGETRFLNNFANTRSFGDVAGK--------PYGI 314

  Fly   484 SALPDI----------------KKLIITPEDEFMVLACDGIWNYMSSEEVVEFVRCRLKD-NKKL 531
            |:.|||                .||....::.|:.|..|||.|.::.:|||:.:...:.. ..|.
Yeast   315 SSEPDIFSFLVGNTLHLPRSERSKLPFNGDECFLALVTDGITNKLADQEVVDLITSTVNSWGLKK 379

  Fly   532 ST---ICEELFDNCLAPNTMGDGTGCDNMTAVIVQFKK--KLQELQSTIPPNQTEDKLLKTSEN 590
            :|   :.||......|..|...    ||.|.|:|:...  ....:..|.|  |.|.||:....|
Yeast   380 ATPQFVAEETIKFIQAIATKHS----DNATCVVVRLSNWGNWPNVDRTGP--QRETKLMNAQSN 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10417	NP_610169.1	PP2Cc	18..>100	CDD:214625
CG10417	NP_610169.1	PP2Cc	<374..564	CDD:238083	54/238 (23%)
PTC6	NP_010003.2	PP2C	108..401	CDD:395385	65/322 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900