DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10417 and KAPP

DIOPT Version :9

Sequence 1:	NP_610169.1	Gene:	CG10417 / 35492	FlyBaseID:	FBgn0033021	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001154720.1	Gene:	KAPP / 832048	AraportID:	AT5G19280	Length:	591	Species:	Arabidopsis thaliana

Alignment Length:	557	Identity:	126/557 - (22%)
Similarity:	203/557 - (36%)	Gaps:	146/557 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 LQEESNL---PLNEVLEKY--KGLPQKKDLDLKSS-----DHKENFKMRSPYFRGRRAAAL--AA 188
            :.::.||   ..:||..:|  :|...:.|..|.||     .:|:.....||:|....:..|  .:
plant    57 ISDDGNLIQGQTSEVTREYDLEGACYQNDGLLHSSLTEGRFYKQRLPSSSPHFSQGESFVLEVIS 121

  Fly   189 EATNKAVMDPSAKPDGSSTSAAAAAAALSADGVANSRNPS--------NVVN------------- 232
            |.::.|::..:.|......|    .|.:......|:||.:        .::|
plant   122 EPSDNALVGQTLKLPAEKGS----LAEVQTYDWQNNRNENLQYNLEKDRLINLSPRLVEDQRSWL 182

  Fly   233 -------PMAGADS--NTTTS------INDLSTKNAALKDDSVNDQNEGS--NGTDFKHTLV--S 278
                   |..|...  |:|:|      :..:|..:.||||..|:.::...  |.|.||..||  .
plant   183 FLEVIAGPAIGLQHAVNSTSSSKLPVKLGRVSPSDLALKDSEVSGKHAQITWNSTKFKWELVDMG 247

  Fly   279 SSNKKLFATGSNDMTELNQ---------SSKNEFTNSSTSKEFERNINSSQDDEF---------T 325
            |.|..|..:.|....:|..         :|.:..|..:|:|.:   :..|..:||         :
plant   248 SLNGTLVNSHSISHPDLGSRKWGNPVELASDDIITLGTTTKVY---VRISSQNEFQIPFKIGVAS 309

  Fly   326 DDDA--------DYEENDNVKSPDTSSAESSDCTENDDDGDEDGNE---------------DSDE 367
            |..|        ..|:..:.|.|...:.:.......|..|.....:               ||..
plant   310 DPMAMRRGGRKLPMEDVCHYKWPLPGANKFGLFCVCDGHGGSGAAQSAIKIIPEVLANILSDSLR 374

  Fly   368 EE-----TDEDQMANDNFCANMIE-EPGKDSGCTAVVCLLQGRD------LYVANAGDSRCVISR 420
            :|     .|...:..|.|...... |..:..||||.| ||..:|      ...||.|||.|||..
plant   375 KEKVLSKRDASDVLRDMFAKTEARLEEHQYEGCTATV-LLVWKDNEENFFAQCANLGDSACVIQN 438

  Fly   421 ----------SGQAIEMSIDHKPEDDEEASRIIKAGGRVTLDGRVN-GGLNLSRALGDHAYKTNV 474
                      .|:.|:|:.||:.....|..|..:| |....||... .|:||:|.|||...|
plant   439 KDLACLKRDLGGRYIQMTEDHRVVSLSERKRFQEA-GLALRDGETRLFGINLARMLGDKFPK--- 499

  Fly   475 TLPAEEQMISALPDIK---KLIITPEDEFMVLACDGIWNYMSSEEVVEFVRCRLKDNKK-----L 531
               .::...||.|.|.   ::..:.:|.|.|||.||:|:.:|.::.|:.| .:::|.::     .
plant   500 ---QQDSRFSAEPYISEPLRIDQSSKDVFAVLASDGLWDVVSPKKAVQLV-LQMRDKERGRESSA 560

  Fly   532 STICEELFDNCLAPNTMGDGTGCDNMTAVIVQFKKKL 568
            ..|...|.:...|..|.      ||.:.:.:.|...|
plant   561 EKIANGLLNEARAMRTK------DNTSIIYLDFDTSL 591

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10417	NP_610169.1	PP2Cc	18..>100	CDD:214625
CG10417	NP_610169.1	PP2Cc	<374..564	CDD:238083	60/215 (28%)
KAPP	NP_001154720.1	FHA	181..295	CDD:238017	26/116 (22%)
		FHA	<211..296	CDD:224630	22/87 (25%)
		PP2C	309..580	CDD:278884	70/285 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900