Protein Alignment CG10417 and PPM1A

DIOPT Version :9

• Sequence 1: NP_610169.1
• Gene: CG10417 / 35492
• FlyBaseID: FBgn0033021
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_016876870.1
• Gene: PPM1A / 5494
• HGNCID: 9275
• Length: 459
• Species: Homo sapiens
• Alignment Length: 666
• Identity: 138/666 - (20%)
• Similarity: 202/666 - (30%)
• Gaps: 308/666 - (46%)

  Fly     1 MGAYLSHPKTDKTSTDQFNELLAVGASSMQGWRNSQEDAHNSILNFDN---NTSFFAVYDGHGGA 62
            |||:|..||.:|.:.......|..|.|||||||...||||.:::...:   :.|||||||||.|:
Human    78 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGS 142

  Fly    63 EVAQYCADKLPHFLKNLETYKNGQFEVALKEAFLGFDKTLLDPSIVSILKILAGEHNFVDAEADD 127
            :||:||.:.|...:.|.:.:|
Human   143 QVAKYCCEHLLDHITNNQDFK-------------------------------------------- 163

  Fly   128 YEEEDLAELQEESNLPLNEVLEKYKGLPQKKDLDLKSSDHKENFKMRSPYFRGRRAAALAAEATN 192
                                                                             
Human   164 ----------------------------------------------------------------- 163

  Fly   193 KAVMDPSAKPDGSSTSAAAAAAALSADGVANSRNPSNVVNPMAGADSNTTTSINDLSTKNAALKD 257
                              .:|.|.|.:.|.|                         ..:...|:.
Human   164 ------------------GSAGAPSVENVKN-------------------------GIRTGFLEI 185

  Fly   258 DSVNDQNEGSNGTDFKHTLVSSSNKKLFATGSNDMTELNQSSKNEFTNSSTSKEFERNINSSQDD 322
            |              :|..|.|..|.
Human   186 D--------------EHMRVMSEKKH--------------------------------------- 197

  Fly   323 EFTDDDADYEENDNVKSPDTSSAESSDCTENDDDGDEDGNEDSDEEETDEDQMANDNFCANMIEE 387
                                                                             
Human   198 ----------------------------------------------------------------- 197

  Fly   388 PGKD-SGCTAVVCLLQGRDLYVANAGDSRCVISRSGQAIEMSIDHKPEDDEEASRIIKAGGRVTL 451
             |.| ||.|||..|:..:..|..|.||||.::.|:.:....:.||||.:..|..||..|||.|.:
Human   198 -GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMI 261

  Fly   452 DGRVNGGLNLSRALGDHAYKTNVTLPAEEQMISALPDIKKLIITPE-DEFMVLACDGIWNYMSSE 515
            . ||||.|.:||||||..||........||::|..|::..:..:.| |:|::|||||||:.|.:|
Human   262 Q-RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNE 325

  Fly   516 EVVEFVRCRLKDNKKLSTICEELFDNCLAPNTMGDGTGCDNMTAVIVQFK----------KKLQE 570
            |:.:|||.||:....|..:|.|:.|.||...:.      |||:.:::.|.          ||..|
Human   326 ELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSR------DNMSVILICFPNAPKVSPEAVKKEAE 384

  Fly   571 LQSTIPPNQTEDKLLKTSENVSHSLNDQSASKRCASQNADA---DDEILEKNNSKRLKTDLEQEN 632
            |...: ..:.|:.:.|..|.|...::   ..:..||:|..:   ..|:..|.|        ..|.
Human   385 LDKYL-ECRVEEIIKKQGEGVPDLVH---VMRTLASENIPSLPPGGELASKRN--------VIEA 437

  Fly   633 IKDRTPSPSNQNEDPT 648
            :.:|.....|.:.|.|
Human   438 VYNRLNPYKNDDTDST 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10417	NP_610169.1	PP2Cc	18..>100	CDD:214625	30/84 (36%)
		PP2Cc	<374..564	CDD:238083	70/191 (37%)
PPM1A	XP_016876870.1	PP2Cc	100..368	CDD:238083	110/545 (20%)
		PP2C_C	362..437	CDD:285117	15/86 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D957254at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100270
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.720