DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10417 and Ppm1f

DIOPT Version :9

Sequence 1:	NP_610169.1	Gene:	CG10417 / 35492	FlyBaseID:	FBgn0033021	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_786931.1	Gene:	Ppm1f / 287931	RGDID:	631363	Length:	450	Species:	Rattus norvegicus

Alignment Length:	433	Identity:	99/433 - (22%)
Similarity:	159/433 - (36%)	Gaps:	117/433 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 FRGRRAA--ALAAEATNKAVMD------------PSAKPDGSSTSAAAAAAALSADGVANS---- 224
            |.|.|.|  |:||..|::|:..            |..:.:............|.|.|::.|
  Rat    64 FLGSRNAPPAVAAAVTHEAISQLLQTDLSEFKRLPEQEEEEEEEEERVLTTLLDAKGLSRSFFNC 128

  Fly   225 ----------RNPSNVVNPMAGADSNTTTSINDLSTKNAALKDDSVNDQNEGSNGTDFKHT--LV 277
                      |.|.....|    ......||:.:......::|..|       :...|.|.  |.
  Rat   129 LWEVCSQWQKRVPLTAQAP----QRKWLVSIHAIRNTRRKMEDRHV-------SLPAFNHLFGLS 182

  Fly   278 SSSNKKLFAT--GSNDMTELNQSSKNEFTNSSTSKEFERNINSSQDDEFTDDDADYEENDNVKSP 340
            .|.::..||.  |...:.....:|.:..||:           |.|.:..||             |
  Rat   183 DSVHRAYFAVFDGHGGVDAARYASVHVHTNA-----------SHQPELLTD-------------P 223

  Fly   341 DTSSAESSDCTENDDDGDEDGNEDSDEEETDEDQMANDNFCANMIEEPGKD---SGCTAVVCLLQ 402
            ..:..|:...|                     |||        .:::..::   ||.|.|..|:.
  Rat   224 AAALKEAFRHT---------------------DQM--------FLQKAKRERLQSGTTGVCALIT 259

  Fly   403 GRDLYVANAGDSRCVISRSGQAIEMSIDHKPEDDEEASRIIKAGGRVTLDG--RVNGGLNLSRAL 465
            |..|:||..|||:.::.:.||.:::...||||..:|.|||...||.|:|..  ||||.|.:|||:
  Rat   260 GAALHVAWLGDSQVILVQQGQVVKLMEPHKPERQDEKSRIEALGGFVSLMDCWRVNGTLAVSRAI 324

  Fly   466 GDHAYKTNVTLPAEEQMISALPDIKKLIITPEDEFMVLACDGIWNYMSSEEVVEFVRCRLKDNKK 530
            ||         ..::..:|...|.....:|..:::::|||||.::.:...|:...|...|...|.
  Rat   325 GD---------VFQKPYVSGEADAASRELTGLEDYLLLACDGFFDVVPHHEIPGLVHGHLLRQKG 380

  Fly   531 LST-ICEELFDNCLAPNTMGDGTGCDNMTAVIVQFKKKLQELQ 572
            ... :.|||.      ....|....||:|.::|..:..|:.|:
  Rat   381 SGMHVAEELV------AVARDRGSHDNITVMVVFLRDPLELLE 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10417	NP_610169.1	PP2Cc	18..>100	CDD:214625
CG10417	NP_610169.1	PP2Cc	<374..564	CDD:238083	58/195 (30%)
Ppm1f	NP_786931.1	PP2C	151..402	CDD:395385	77/325 (24%)
Ppm1f	NP_786931.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	420..450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900