DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10417 and ptc1

DIOPT Version :9

Sequence 1:	NP_610169.1	Gene:	CG10417 / 35492	FlyBaseID:	FBgn0033021	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_588401.1	Gene:	ptc1 / 2539495	PomBaseID:	SPCC4F11.02	Length:	347	Species:	Schizosaccharomyces pombe

Alignment Length:	400	Identity:	106/400 - (26%)
Similarity:	168/400 - (42%)	Gaps:	97/400 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 PSNVVNPMAGADSNTTTSINDLSTKNAALKDDSVNDQNE--GSNGTDFKHTLVSSSNKKLFATGS 289
            |.:.:||.:   .|:|:.    ..|||:  |.|.:.:..  .....|.|...|...|.:. :..|
pombe    14 PLHKLNPFS---ENSTSG----HRKNAS--DHSADGETRPIAIEMKDSKGNTVPVGNSRP-SKAS 68

  Fly   290 NDMTELNQSSKNEFTNSSTSKEF-ERNINSSQDDEFTDDDADYEENDNVKSPDTSSAESSDCTEN 353
            |.:..|.:.....:..|...... ..:...:|||.|.   |.|:.:..:::.|.       |.:|
pombe    69 NWLAGLMEDKNQRWRRSMEDTHICLYDFGGNQDDGFV---AVYDGHAGIQASDY-------CQKN 123

  Fly   354 DDDGDEDGNEDSDEEETDEDQMANDNFCANMIEEPGKDS--------GCTAVVCLLQ------GR 404
            ..      ....::...:.|::..|......:|...|.:        ||||.|...:      .|
pombe   124 LH------KVLLEKVRNEPDRLVTDLMDETFVEVNSKIAKATHNDICGCTAAVAFFRYEKNRTRR 182

  Fly   405 DLYVANAGDSRCVISRSGQAIEMSIDHKPEDDEEASRIIKAGGRVTLDGRVNGGLNLSRALGDHA 469
            .||.|||||:|.|:.|.|:||.:|.|||..|..|:.|:.:.|| :.:..|:||.|.::|||||..
pombe   183 VLYTANAGDARIVLCRDGKAIRLSYDHKGSDANESRRVTQLGG-LMVQNRINGVLAVTRALGDTY 246

  Fly   470 YKTNVTLPAEEQMISALP-DIKKLIITPEDEFMVLACDGIWNYMSSEEVVEFVR---------CR 524
            .|         :::||.| ..:..|....|||.::||||:|:.:|.:|.|:|||         .|
pombe   247 LK---------ELVSAHPFTTETRIWNGHDEFFIIACDGLWDVVSDQEAVDFVRNFVSPREAAVR 302

  Fly   525 LKD--NKKLSTICEELFDNCLAPNTMGDGTGCDNMTAVIVQFKKKLQELQSTIPPNQTEDKLLKT 587
            |.:  .|:|||                     ||:|.::|...:.         |...:|..| |
pombe   303 LVEFALKRLST---------------------DNITCIVVNLTRN---------PGDLDDSGL-T 336

  Fly   588 SENVSHSLND 597
            ::|.|:| ||
pombe   337 ADNDSYS-ND 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10417	NP_610169.1	PP2Cc	18..>100	CDD:214625
CG10417	NP_610169.1	PP2Cc	<374..564	CDD:238083	69/215 (32%)
ptc1	NP_588401.1	PP2Cc	66..321	CDD:214625	82/301 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I1362
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860