Protein Alignment CG10417 and ppm-1.A

DIOPT Version :10

• Sequence 1: NP_610169.1
• Gene: CG10417 / 35492
• FlyBaseID: FBgn0033021
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_001023842.1
• Gene: ppm-1.A / 179469
• WormBaseID: WBGene00006460
• Length: 468
• Species: Caenorhabditis elegans
• Alignment Length: 668
• Identity: 145/668 - (21%)
• Similarity: 220/668 - (32%)
• Gaps: 296/668 - (44%)

  Fly     1 MGAYLSHPKTDKTSTDQFNELLAVGASSMQGWRNSQEDAH--NSILNFDN---NTSFFAVYDGHG 60
            |||:|..||||||:.......:..|.|||||||...||:|  .:|::..:   :.|||||:|||.
 Worm    84 MGAFLDKPKTDKTNVHGEGNGIRYGMSSMQGWRICMEDSHIAEAIMSQSSPYKDWSFFAVFDGHA 148

  Fly    61 GAEVAQYCADK-LPHFLKNLETYKNGQFEVALKEAFLGFDKTLLDPSIVSILKILAGEHNFVDAE 124
            |..:|...:.: |.|.:.:              |.|....|||
 Worm   149 GHHIANRASSQLLEHLISS--------------EEFREMTKTL---------------------- 177

  Fly   125 ADDYEEEDLAELQEESNLPLNEVLEKYKGLPQKKDLDLKSSDHKENFKMRSPYFRGRRAAALAAE 189
                         ||:|           |:.....|.|.....|:.|
 Worm   178 -------------EENN-----------GVLTDSTLKLLEKGIKKGF------------------ 200

  Fly   190 ATNKAVMDPSAKPDGSSTSAAAAAAALSADGVANSRNPSNVVNPMAGADSNTTTSINDLSTKNAA 254
                                      ||.|.::.:
 Worm   201 --------------------------LSFDEISKT------------------------------ 209

  Fly   255 LKDDSVNDQNEGSNGTDFKHTLVSSSNKKLFATGSNDMTELNQSSKNEFTNSSTSKEFERNINSS 319
                                              |||:::
 Worm   210 ----------------------------------SNDISK------------------------- 215

  Fly   320 QDDEFTDDDADYEENDNVKSPDTSSAESSDCTENDDDGDEDGNEDSDEEETDEDQMANDNFCANM 384
                                                                             
 Worm   216 ----------------------------------------------------------------- 215

  Fly   385 IEEPGKDSGCTAVVCLLQGRDLYVANAGDSRCVISRSGQAIEMSIDHKPEDDEEASRIIKAGGRV 449
                   ||||||..::......:.|.||||.|::...: |..:.||||..::|..||..|||.|
 Worm   216 -------SGCTAVCAIVTPTHFIIGNLGDSRAVVAGKNE-IFGTEDHKPYLEKERKRIEGAGGSV 272

  Fly   450 TLDGRVNGGLNLSRALGDHAYKTNVTLPAEEQMISALPDI----KKLIITPEDEFMVLACDGIWN 510
            .:. |:||.|.:|||.||:.||.:..|||::|::|..||:    :.|   ..|:|||:|||||::
 Worm   273 MIQ-RINGSLAVSRAFGDYEYKDDPRLPADQQLVSPEPDVYIRERNL---ENDQFMVVACDGIYD 333

  Fly   511 YMSSEEVVEFVRCRLKDNKKLSTICEELFDNCLAPNTMGDGTGCDNMTAVIVQFKKKLQELQSTI 575
            .|::||:.|||:.||..:..|..:|:::.|.||...:.      ||||.|:|.|.   ...:..|
 Worm   334 VMTNEELAEFVKDRLSVHSDLREVCDDVLDECLVKGSR------DNMTMVVVCFP---AAPEVNI 389

  Fly   576 PPNQTEDKLLKTSENVSHSLNDQSASKRCASQNAD--ADDEILEKNNSK-RLKTDLEQENIKDRT 637
            ...:.|:..:...:.|.:...|::.:.....|..|  ....||:|..:. .|.|||   .:.:.|
 Worm   390 HRKEAEEAWVSRVKTVINQFLDEAVAAEDFKQEEDMVTLKSILDKVTANGLLPTDL---RVPEHT 451

  Fly   638 PSPSNQNEDPTQKAIKEV 655
            .:...| :..||:.||.|
 Worm   452 VTTLAQ-KILTQRDIKHV 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10417	NP_610169.1	PP2Cc	18..>100	CDD:214625	26/87 (30%)
		PP2Cc	<374..564	CDD:238083	71/193 (37%)
ppm-1.A	NP_001023842.1	PP2C	105..374	CDD:395385	109/544 (20%)
		PP2C_C	375..>414	CDD:429684	8/41 (20%)