DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10417 and PPM1L

DIOPT Version :9

Sequence 1:NP_610169.1 Gene:CG10417 / 35492 FlyBaseID:FBgn0033021 Length:662 Species:Drosophila melanogaster
Sequence 2:NP_640338.2 Gene:PPM1L / 151742 HGNCID:16381 Length:360 Species:Homo sapiens


Alignment Length:349 Identity:99/349 - (28%)
Similarity:155/349 - (44%) Gaps:79/349 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   270 TDFKHTLVSSS----------------NKKLFATGSNDMTELNQSSKNEFTNSSTSKEFERNINS 318
            ||...|:|.||                |.:|   |..|:.|...|...||.|.:.:....:....
Human    42 TDEVKTIVKSSRDAVKMVKGKVAEIMQNDRL---GGLDVLEAEFSKTWEFKNHNVAVYSIQGRRD 103

  Fly   319 SQDDEF---TD-------------------DDADYEENDNVKS--PDTSSAESSDCTENDDDGDE 359
            ..:|.|   ||                   ..|:|     |||  |:.......|.     :.|:
Human   104 HMEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEY-----VKSRLPEALKQHLQDY-----EKDK 158

  Fly   360 DGNEDSDEEETDEDQMANDNFCANMIEEPGKDSGCTAVVCLLQGRDLYVANAGDSRCVI-SRSGQ 423
            :.:..|.:...::..::.|......:.....::|.|.::.||..:||.|||.||||.|: .:.|.
Human   159 ENSVLSYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGN 223

  Fly   424 AIEMSIDHKPEDDEEASRIIKAGGRVTLDG--RVNGGLNLSRALGDHAYKT-NVTLPAEEQMISA 485
            ||.:|.||||...:|..||.:|||.::.:|  ||.|.|.:||:|||:..|. ||.:|..:.:.. 
Human   224 AIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTF- 287

  Fly   486 LPDIKKLIITPEDEFMVLACDGIWNYMSSEEVVEFVRCRLKDNK--KLSTICEELFDNCLAPNTM 548
              |:.||    :.|||:||.||:|:..|:||.|.|::.||.:..  ..|.:.:..:..|  |   
Human   288 --DLDKL----QPEFMILASDGLWDAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGC--P--- 341

  Fly   549 GDGTGCDNMTAVIVQFK--KKLQE 570
                  ||:|.::|:|:  .|.:|
Human   342 ------DNITVMVVKFRNSSKTEE 359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10417NP_610169.1 PP2Cc 18..>100 CDD:214625
PP2Cc <374..564 CDD:238083 68/195 (35%)
PPM1LNP_640338.2 PP2Cc 93..351 CDD:238083 81/285 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0631
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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