DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment COX4L and Cox4i2

DIOPT Version :9

Sequence 1:	NP_610168.1	Gene:	COX4L / 35491	FlyBaseID:	FBgn0033020	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	XP_017447568.1	Gene:	Cox4i2 / 84683	RGDID:	69422	Length:	233	Species:	Rattus norvegicus

Alignment Length:	129	Identity:	44/129 - (34%)
Similarity:	71/129 - (55%)	Gaps:	4/129 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 FDSPDCPFPAIRYREVSPELCALREKELDDWKKLSLDEKKQLYRYSFCQTYAEFQHITPEWKMCL 112
            :..||.|:    ..|:|.|..||:|||...|.:||..||..|||..|.:|:||..|.:.|||..:
  Rat   108 YPMPDEPY----CTELSEEQRALKEKEKGSWAQLSQAEKVALYRLQFHETFAEMNHRSNEWKTVM 168

  Fly   113 GVALWLVSIGIAISITMKTVLYGKLPDTFNDERQSAQLRRIIQLQMNPITGLASKWCYRENKWK 176
            |...:.:.....:....:..::.|...|..:||::.||:|::.::.|||.||::.|.|.:.:||
  Rat   169 GCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLSAHWDYEKKEWK 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
COX4L	NP_610168.1	COX4	45..176	CDD:281003	42/127 (33%)
Cox4i2	XP_017447568.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344991
Domainoid	1	1.000	108	1.000	Domainoid score	I6289
eggNOG	1	0.900	-	-		E1_KOG4075
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I4813
OMA	1	1.010	-	-		QHG48902
OrthoDB	1	1.010	-	-		D1591226at2759
OrthoFinder	1	1.000	-	-		FOG0002054
OrthoInspector	1	1.000	-	-		mtm9068
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10707
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X922
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.870