DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment COX4L and Apobec3

DIOPT Version :9

Sequence 1:	NP_610168.1	Gene:	COX4L / 35491	FlyBaseID:	FBgn0033020	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_001028875.1	Gene:	Apobec3 / 315137	RGDID:	1307800	Length:	385	Species:	Rattus norvegicus

Alignment Length:	148	Identity:	38/148 - (25%)
Similarity:	51/148 - (34%)	Gaps:	45/148 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LRKLFQMT------RRRFASG-----------GDGIRLMVADRQVV----GH---------GING 43
            |:||:|.|      ..|:|.|           |....|.|..||.|    ||         ..:.
  Rat    21 LKKLYQQTFYFHFKNVRYAWGRKNNFLCYEVNGMDCALPVPLRQGVFRKQGHIHAELCFIYWFHD 85

  Fly    44 RPIYFDSPDCPFPAIRYREVSP-ELCALR-EKELDDWKKLSLD-EKKQLYRY--------SFCQT 97
            :.:...||...|....|...|| ..||.: .:.|...:.|||. ...:||.|        ..|:.
  Rat    86 KVLRVLSPMEEFKVTWYMSWSPCSKCAEQVARFLAAHRNLSLAIFSSRLYYYLRNPNYQQKLCRL 150

  Fly    98 YAEFQHIT----PEWKMC 111
            ..|..|:.    ||:|.|
  Rat   151 IQEGVHVAAMDLPEFKKC 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
COX4L	NP_610168.1	COX4	45..176	CDD:281003	22/82 (27%)
Apobec3	NP_001028875.1	APOBEC_N	29..199	CDD:285428	33/140 (24%)
		cytidine_deaminase	<71..150	CDD:238610	18/78 (23%)
		APOBEC_C	141..186	CDD:283020	7/28 (25%)
		APOBEC_N	212..378	CDD:285428
		cytidine_deaminase	226..332	CDD:238610
		APOBEC_C	322..365	CDD:283020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900