DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment COX4L and Cox4i1

DIOPT Version :9

Sequence 1:	NP_610168.1	Gene:	COX4L / 35491	FlyBaseID:	FBgn0033020	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_058898.1	Gene:	Cox4i1 / 29445	RGDID:	68374	Length:	169	Species:	Rattus norvegicus

Alignment Length:	133	Identity:	51/133 - (38%)
Similarity:	81/133 - (60%)	Gaps:	1/133 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 PIYFDSPDCPFPAIRY-REVSPELCALREKELDDWKKLSLDEKKQLYRYSFCQTYAEFQHITPEW 108
            |.|.|..|.|.|.:.: :.:|....||:|||..||..||.|||.||||..|.:::||....|.||
  Rat    36 PSYVDRRDYPLPDVAHVKLLSASQKALKEKEKADWSSLSRDEKVQLYRIQFNESFAEMNKGTNEW 100

  Fly   109 KMCLGVALWLVSIGIAISITMKTVLYGKLPDTFNDERQSAQLRRIIQLQMNPITGLASKWCYREN 173
            |..:|:|::.:.....:.|..|:.:||.:|.||:.:..:.|.:|::.:::|||.|.::||.|.:|
  Rat   101 KTVVGLAMFFIGFTALVLIWEKSYVYGPIPHTFDRDWVAMQTKRMLDMKVNPIQGFSAKWDYNKN 165

  Fly   174 KWK 176
            :||
  Rat   166 EWK 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
COX4L	NP_610168.1	COX4	45..176	CDD:281003	49/131 (37%)
Cox4i1	NP_058898.1	COX4	36..168	CDD:397197	49/131 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344989
Domainoid	1	1.000	108	1.000	Domainoid score	I6289
eggNOG	1	0.900	-	-		E1_KOG4075
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37537
Inparanoid	1	1.050	108	1.000	Inparanoid score	I4813
OMA	1	1.010	-	-		QHG48902
OrthoDB	1	1.010	-	-		D1591226at2759
OrthoFinder	1	1.000	-	-		FOG0002054
OrthoInspector	1	1.000	-	-		mtm9068
orthoMCL	1	0.900	-	-		OOG6_103849
Panther	1	1.100	-	-	O	PTHR10707
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X922
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770