Protein Alignment CG10395 and INO80B

DIOPT Version :10

• Sequence 1: NP_610167.3
• Gene: CG10395 / 35490
• FlyBaseID: FBgn0033019
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_112578.2
• Gene: INO80B / 83444
• HGNCID: 13324
• Length: 356
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 91/287 - (31%)
• Similarity: 126/287 - (43%)
• Gaps: 53/287 - (18%)

  Fly     1 MVKEGSKDAEYLSAESISNSLRPKE---LHYTTDALASNSNIHEHPLRRTRNISTKKLAHDDSLP 62
            ::.||.:....|..  :.|...|.|   |......|..:||:...|||..
Human    90 VIPEGPRSPSPLMV--VDNEEEPMEGVPLEQYRAWLDEDSNLSPSPLRDL--------------- 137

  Fly    63 HTGAKKGKRRRNSDTSSEEDRWLTAIETGKLDVVDEELKKIKDPKLMTARQRAIYE--RTQDSEI 125
             :|...|:.      ..||.|||.|:|.|:|| .:.:|||..:.:|:||||||:.:  |:|.|.:
Human   138 -SGGLGGQE------EEEEQRWLDALEKGELD-DNGDLKKEINERLLTARQRALLQKARSQPSPM 194

  Fly   126 NGFIEELIALPSGYKEKEKPQ--TAEEIHKALLKSQKRKQQADERREKDKLKTMERLLKKQATN- 187
                     ||....|...|.  |.|.:.|...:::||:.||..|.|:.|.:|:|||.|..||:
Human   195 ---------LPLPVAEGCPPPALTEEMLLKREERARKRRLQAARRAEEHKNQTIERLTKTAATSG 250

  Fly   188 -----RDRISIRNKSLQQPSYPKITYISAVTGNYVIVPPGYEYPLKVQ---LPRTPPPSQVCFVS 244
                 ..|...|......|: |.:.|.|...|:.:..|||...|..|.   .|..|||.  |.|.
Human   251 RGGRGGARGERRGGRAAAPA-PMVRYCSGAQGSTLSFPPGVPAPTAVSQRPSPSGPPPR--CSVP 312

  Fly   245 GCENRKTYNCSTTNVPLCSLTCYRKNI 271
            ||.:.:.|.||.|...||||.|||.|:
Human   313 GCPHPRRYACSRTGQALCSLQCYRINL 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10395	NP_610167.3	PAPA-1	157..220	CDD:461431	21/68 (31%)
		zf-HIT_IN80B	241..271	CDD:467793	15/29 (52%)
INO80B	NP_112578.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..150		8/47 (17%)
		PAPA-1	211..287	CDD:461431	23/76 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..269		4/22 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	286..310		9/25 (36%)
		zf-HIT_IN80B	309..339	CDD:467793	15/29 (52%)