Protein Alignment CG10465 and Kctd10

DIOPT Version :10

• Sequence 1: NP_610165.1
• Gene: CG10465 / 35488
• FlyBaseID: FBgn0033017
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: NP_001153413.1
• Gene: Kctd10 / 330171
• MGIID: 2141207
• Length: 316
• Species: Mus musculus
• Alignment Length: 308
• Identity: 196/308 - (63%)
• Similarity: 229/308 - (74%)
• Gaps: 25/308 - (8%)

  Fly     3 ESMSGDHKI------------LLKG--HSSQYLKLNVGGHLYYTTIGTLTKNNDTMLSAMFSGRM 53
            |.||||..:            ..||  .||:|:||||||.|||||:.|||| .||||.|||||||
Mouse     2 EEMSGDSVVSSAVPAAATRTTSFKGASPSSKYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRM 65

  Fly    54 EVLTDSEGWILIDRCGNHFGIILNYLRDGTVPLPETNKEIAELLAEAKYYCITELAISCERALYA 118
            ||||||||||||||||.|||.||||||||.|||||:.:||.|||||||||.:..|...|:.||..
Mouse    66 EVLTDSEGWILIDRCGKHFGTILNYLRDGGVPLPESRREIEELLAEAKYYLVQGLLEECQAALQQ 130

  Fly   119 HQEP-KPICRIPLITSQKEEQLLLSVSLKPAVILVVQRQNNKYSYTSTSDDNLLKNIELFDKLSL 182
            :::. :|.|::|:|||.||||.|::.|.||||.|:..|.||||||||.||||:||||||||||||
Mouse   131 NKDTYEPFCKVPVITSSKEEQRLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSL 195

  Fly   183 RFNERILFIKDVIGPSEICCWSFYGHGKKVAEVCCTSIVYATDRKHTKVEFPEARIYEETLQVLL 247
            |||.|:|||||||| .|||||||||.|:|:||||||||||||::|.|||||||||||||||.:||
Mouse   196 RFNGRVLFIKDVIG-DEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILL 259

  Fly   248 YENRN--APDQELMQATSSARVGSASGTSINQYTSDEEEERTGLARLR 293
            ||.::  .||..|::||     |.|:|.| :....|||.||..:.|:|
Mouse   260 YEAQDGRGPDNALLEAT-----GGAAGRS-HHLDEDEERERERIERVR 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10465	NP_610165.1	BTB_POZ_KCTD10-like_BACURD	21..112	CDD:349678	70/90 (78%)
Kctd10	NP_001153413.1	BTB_POZ_KCTD10_BACURD3	26..136	CDD:349707	77/110 (70%)
		PCNA-binding. /evidence=ECO:0000250	240..246		4/5 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..295		11/30 (37%)