Protein Alignment CG10465 and KCTD1

DIOPT Version :10

• Sequence 1: NP_610165.1
• Gene: CG10465 / 35488
• FlyBaseID: FBgn0033017
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: NP_001136202.1
• Gene: KCTD1 / 284252
• HGNCID: 18249
• Length: 865
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 65/278 - (23%)
• Similarity: 113/278 - (40%)
• Gaps: 70/278 - (25%)

  Fly    17 SSQYLKLNVGGHLYYTTIGTLTKNNDTMLSAMFSGRMEVLTDS-EGWILIDRCGNHFGIILNYLR 80
            |:..:.::||||:|.:::.||||..::.:..:|.|...::.|| :....|||.|..|..|||:||
Human   636 SNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLR 700

  Fly    81 DGTVPLPETNKEIAELLAEAKYYCITELAISCERALYAHQEPKPICRIPLITSQKEEQLLLSVSL 145
            ...:.:|:..|:...|..||||:.:..:.:..||                 ..|..|....|
Human   701 TSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMER-----------------WKQDRETGRFS--- 745

  Fly   146 KPAVILVVQRQNNKYSYTSTSDDNLLKNIELFDKLSLRFNERILFIKDVIGPSEICCWSFYGHGK 210
            :|...|||:          .:.|       |.::::|..::.:  |::|.              .
Human   746 RPCECLVVR----------VAPD-------LGERITLSGDKSL--IEEVF--------------P 777

  Fly   211 KVAEVCCTSIVYATDRKHTKV-EFP-EARIYEETLQVLLYENRNAPDQELMQATSSARVGSASG- 272
            ::.:|.|.|:....:...|.| .|| ....:..::|||          |.:|......|||..|
Human   778 EIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLNSVQVL----------ERLQQRGFEIVGSCGGG 832

  Fly   273 ---TSINQYTSDEEEERT 287
               :..::|....|..||
Human   833 VDSSQFSEYVLRRELRRT 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10465	NP_610165.1	BTB_POZ_KCTD10-like_BACURD	21..112	CDD:349678	30/91 (33%)
KCTD1	NP_001136202.1	DUF3504	284..440	CDD:463430
		BTB_POZ_KCTD1	636..740	CDD:349695	34/120 (28%)
		H1_KCTD12-like	<762..845	CDD:425358	20/108 (19%)