DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10465 and Kctd13

DIOPT Version :9

Sequence 1:	NP_610165.1	Gene:	CG10465 / 35488	FlyBaseID:	FBgn0033017	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_766335.1	Gene:	Kctd13 / 233877	MGIID:	1923739	Length:	329	Species:	Mus musculus

Alignment Length:	271	Identity:	170/271 - (62%)
Similarity:	208/271 - (76%)	Gaps:	9/271 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SSQYLKLNVGGHLYYTTIGTLTKNNDTMLSAMFSGRMEVLTDSEGWILIDRCGNHFGIILNYLRD 81
            :|:|:||||||.|:|||:.||| ..||||.||||||:|||||:.||:||||.|.|||.|||||||
Mouse    39 NSKYVKLNVGGSLHYTTLRTLT-GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRD 102

  Fly    82 GTVPLPETNKEIAELLAEAKYYCITELAISCERALYAHQEP-KPICRIPLITSQKEEQLLLSVSL 145
            |:|||||:.:|:.|||.||:||.:..|...|:.||...:|. .|:|.||.:||.:|||.||:.:.
Mouse   103 GSVPLPESARELGELLGEARYYLVQGLIEDCQLALQQKREKLSPLCLIPTVTSPREEQQLLASTS 167

  Fly   146 KPAVILVVQRQNNKYSYTSTSDDNLLKNIELFDKLSLRFNERILFIKDVIGPSEICCWSFYGHGK 210
            ||.|.|:..|.||||||||||||||||||||||||:|||:.|:||:|||:| .|||||||||.|:
Mouse   168 KPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLG-DEICCWSFYGQGR 231

  Fly   211 KVAEVCCTSIVYATDRKHTKVEFPEARIYEETLQVLLYENRNAPDQELMQATSSARVGSASGTSI 275
            |:||||||||||||::|.||||||||||:||||.:|:|||...||..|::||..|..|..:|
Mouse   232 KIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYENSRGPDLALLEATGGAAGGGGAG--- 293

  Fly   276 NQYTSDEEEER 286
               ..|:||.|
Mouse   294 ---RGDDEENR 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10465	NP_610165.1	BTB	20..117	CDD:197585	63/96 (66%)
CG10465	NP_610165.1	BTB_2	21..112	CDD:280393	60/90 (67%)
Kctd13	NP_766335.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
		BTB	42..141	CDD:197585	64/99 (65%)
		BTB	43..133	CDD:295341	60/90 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832153
Domainoid	1	1.000	221	1.000	Domainoid score	I2587
eggNOG	1	0.900	-	-		E1_KOG2716
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	365	1.000	Inparanoid score	I2147
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48414
OrthoDB	1	1.010	-	-		D1306250at2759
OrthoFinder	1	1.000	-	-		FOG0001839
OrthoInspector	1	1.000	-	-		otm44338
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11145
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5106
SonicParanoid	1	1.000	-	-		X185
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.900