DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10465 and D2045.8

DIOPT Version :9

Sequence 1:	NP_610165.1	Gene:	CG10465 / 35488	FlyBaseID:	FBgn0033017	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_499312.2	Gene:	D2045.8 / 176468	WormBaseID:	WBGene00008425	Length:	238	Species:	Caenorhabditis elegans

Alignment Length:	244	Identity:	75/244 - (30%)
Similarity:	123/244 - (50%)	Gaps:	51/244 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SQYLKLNVGGHLYYTTIGTLTKNNDTMLSAMFSGRMEVLTDSEGWILIDRCGNHFGIILNYLRDG 82
            |..:||:|||.::.|||.||.| :|:||..||...:.|..:.||.:.|||...||.:|||:||||
Worm     4 STIVKLDVGGKIFKTTIFTLCK-HDSMLKTMFCTDVPVTKNEEGSVFIDRDSKHFRLILNFLRDG 67

  Fly    83 TVPLPETNKEIAELLAEAKYYCITELAISC----ERAL--YAHQEPKPICRIPLITSQKEEQLLL 141
            .:.||::::|:.|:||||.|:.:..|...|    |::|  |.|          |:::..|.:.::
Worm    68 QIALPDSDREVREVLAEASYFLLDPLIELCGERLEQSLNPYYH----------LVSTVLEARKII 122

  Fly   142 SVSLKPAVIL-----VVQRQNNKYSYTSTSDDNLLKNIELFDKLSLRFNERILFIKDVIGP--SE 199
            ..:.||.|:|     :....|..|.::.|.          |.:||..:::.:.||. :..|  :|
Worm   123 FATEKPIVVLRLPVYIATSGNQSYYFSETK----------FRELSEEYHKHVAFIL-ITEPEFNE 176

  Fly   200 ICCWSFYGHGKKVAEVCCTSIVYATDRKHTKVEFP-EARIYEETLQVLL 247
            .|.|||:...||:.               .:::.| :..:.||.:|.||
Worm   177 DCSWSFFLRAKKIT---------------ARIKGPMDCNLVEECMQKLL 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10465	NP_610165.1	BTB	20..117	CDD:197585	44/102 (43%)
CG10465	NP_610165.1	BTB_2	21..112	CDD:280393	41/90 (46%)
D2045.8	NP_499312.2	BTB_POZ	7..97	CDD:365784	41/90 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	83	1.000	Domainoid score	I5330
eggNOG	1	0.900	-	-		E1_KOG2716
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32652
Inparanoid	1	1.050	102	1.000	Inparanoid score	I3561
Isobase	1	0.950	-	0	Normalized mean entropy	S3463
OMA	1	1.010	-	-		QHG48414
OrthoDB	1	1.010	-	-		D1306250at2759
OrthoFinder	1	1.000	-	-		FOG0001839
OrthoInspector	1	1.000	-	-		otm14116
orthoMCL	1	0.900	-	-		OOG6_108166
Panther	1	1.100	-	-	LDO	PTHR11145
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5106
SonicParanoid	1	1.000	-	-		X185
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.820