DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sxc and CG4341

DIOPT Version :9

Sequence 1:	NP_523620.1	Gene:	sxc / 35486	FlyBaseID:	FBgn0261403	Length:	1059	Species:	Drosophila melanogaster
Sequence 2:	NP_608558.1	Gene:	CG4341 / 33276	FlyBaseID:	FBgn0028481	Length:	938	Species:	Drosophila melanogaster

Alignment Length:	492	Identity:	127/492 - (25%)
Similarity:	192/492 - (39%)	Gaps:	98/492 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PNSTGSNLV-----VKQNDIQSLSSVGLLELAHREYQAVDY-ESAEKHCMQLWRQDSTNTGVLLL 89
            |....|||:     |....:..|.|||...|       |.| .|....|.|..|      .:|||
  Fly   515 PFLPASNLLFYVGFVVAERLLYLPSVGFCLL-------VGYGVSKLMSCNQRTR------NILLL 566

  Fly    90 LSSI---HFQCRRLDKSAQF--------STLAIKQNPVLAEAYSNLGNVFKERGQLQEALDNYRR 143
            ..|:   ....|.|.::|.:        |.:||  ||  .:|..|||:|...:|:.:||....:.
  Fly   567 SFSLLLAAMSLRTLRRNADWRDEESLYRSAIAI--NP--PKALGNLGSVLSSQGRYEEAKQVLQE 627

  Fly   144 AVRLKPDFIDGYINLAAALVAARDMESAVQAYITALQYNPDLYCVRSDLGNLLKALGRLEEAKAC 208
            |:|.:|:..|.:.||.                  .|..|..:|                ..|..|
  Fly   628 AIRFRPNMADVHFNLG------------------ILHQNQQVY----------------PAAVEC 658

  Fly   209 YLKAIETCPGFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRA 273
            :.:||:..|..|||:.|||..|.|.|:...||...:....||          |..:::....|:|
  Fly   659 FQRAIKFRPNLAVAYLNLGISFIALGKRQQAIEILQAGSNLD----------GAAVRDRTAHDQA 713

  Fly   274 -VAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPD----AYCNLANALK 333
             .:|||:              |..:|.|||.:..|:..||.|:...|..|.    .|..:.:.|.
  Fly   714 RSSAYLQ--------------LGALYVEQGKLQRALAIYREALSSLPGLPQQREILYQRIGDVLG 764

  Fly   334 EKGQVKEAEDCYNTALRLCSNH-ADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLA 397
            ...|..|||..:..||.|..|. |..|:....:.|......||...:.:||::.|:.|:.:.:.|
  Fly   765 RLQQWDEAERHHRAALELQPNQVAAHLSYGITLARNSSRASEAEMWFKRALKLAPEQASVYHHYA 829

  Fly   398 SVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHS 462
            ..|..|.:..|:.::::.|..:.|............::.|.....|...|.:|:.:.|..|.||:
  Fly   830 EFLSLQSRHHESAIYHRRAAELAPNDYTLVVAAATAMRLLDRKVDAEMWYRKAVALRPGDAHAHT 894

  Fly   463 NLASIHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLA 499
            ||.:|....|....|..||:.||:|:|.......|||
  Fly   895 NLGAILHLLGRTNHAAASYKAALRLQPGDAITLGNLA 931

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sxc	NP_523620.1	TPR repeat	53..78	CDD:276809	6/25 (24%)
		TPR_11	86..149	CDD:290150	22/73 (30%)
		TPR repeat	86..112	CDD:276809	9/36 (25%)
		TPR_11	118..183	CDD:290150	15/64 (23%)
		TPR_1	118..151	CDD:278916	11/32 (34%)
		TPR repeat	118..146	CDD:276809	9/27 (33%)
		TPR repeat	151..181	CDD:276809	4/29 (14%)
		TPR_12	182..252	CDD:290160	20/69 (29%)
		TPR_1	192..219	CDD:278916	5/26 (19%)
		TPR_1	220..253	CDD:278916	13/32 (41%)
		TPR repeat	220..248	CDD:276809	11/27 (41%)
		TPR	233..490	CDD:223533	65/262 (25%)
		TPR_1	255..287	CDD:278916	6/32 (19%)
		TPR repeat	255..282	CDD:276809	6/27 (22%)
		TPR repeat	287..317	CDD:276809	9/29 (31%)
		TPR_1	288..321	CDD:278916	10/32 (31%)
		TPR_17	310..342	CDD:290167	9/35 (26%)
		TPR repeat	322..350	CDD:276809	8/31 (26%)
		TPR repeat	355..385	CDD:276809	7/30 (23%)
		TPR_10	356..>385	CDD:290111	7/28 (25%)
		TPR_1	390..423	CDD:278916	7/32 (22%)
		TPR repeat	390..418	CDD:276809	6/27 (22%)
		TPR repeat	423..453	CDD:276809	4/29 (14%)
		TPR_1	424..455	CDD:278916	4/30 (13%)
		TPR_1	458..491	CDD:278916	14/32 (44%)
		TPR repeat	458..486	CDD:276809	11/27 (41%)
		Glyco_transf_41	584..1044	CDD:290556
CG4341	NP_608558.1	PMT_2	112..>232	CDD:304453
		DUF1736	275..343	CDD:285594
		TPR_11	602..667	CDD:290150	21/98 (21%)
		TPR_1	602..634	CDD:278916	10/31 (32%)
		TPR repeat	602..630	CDD:276809	9/27 (33%)
		TPR repeat	635..665	CDD:276809	10/63 (16%)
		TPR_11	636..700	CDD:290150	22/97 (23%)
		TPR_1	636..668	CDD:278916	10/65 (15%)
		TPR repeat	670..694	CDD:276809	11/23 (48%)
		TPR_11	714..784	CDD:290150	23/83 (28%)
		TPR repeat	715..743	CDD:276809	12/41 (29%)
		TPR repeat	748..782	CDD:276809	9/33 (27%)
		TPR_11	755..819	CDD:290150	17/63 (27%)
		TPR repeat	787..816	CDD:276809	6/28 (21%)
		TPR_11	821..887	CDD:290150	11/65 (17%)
		TPR repeat	822..850	CDD:276809	6/27 (22%)
		TPR repeat	855..885	CDD:276809	4/29 (14%)
		TPR_11	<874..921	CDD:290150	17/46 (37%)
		TPR repeat	890..918	CDD:276809	11/27 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467053
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840