DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment d4 and ESA1

DIOPT Version :9

Sequence 1:NP_610163.1 Gene:d4 / 35485 FlyBaseID:FBgn0033015 Length:497 Species:Drosophila melanogaster
Sequence 2:NP_014887.3 Gene:ESA1 / 854418 SGDID:S000005770 Length:445 Species:Saccharomyces cerevisiae


Alignment Length:110 Identity:27/110 - (24%)
Similarity:40/110 - (36%) Gaps:28/110 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   117 NLQHSHHQTHQHHHHIP---SSGVAVPQNPHLAESAAIAATDGNSMGASGDNDSKDSHANVEKE- 177
            |:|....:...|...|.   :|| ::.||||  |.|.:...:...||            ..|.| 
Yeast   130 NVQGIKDENISHEDEIKKLRTSG-SMTQNPH--EVARVRNLNRIIMG------------KYEIEP 179

  Fly   178 WFHD----EMDTSHFHHGDEFEDDFDSDNDFDESYTSRGKRKKCS 218
            |:..    |:....|.:.|:|...:.......|.|     ||||:
Yeast   180 WYFSPYPIELTDEDFIYIDDFTLQYFGSKKQYERY-----RKKCT 219

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
d4NP_610163.1 Requiem_N 30..98 CDD:290758
PHD1_d4 387..442 CDD:277091
PHD2_d4 444..489 CDD:277005
ESA1NP_014887.3 SAS2 16..431 CDD:227360 27/110 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C157345438
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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