Protein Alignment d4 and DPF1

DIOPT Version :10

• Sequence 1: NP_610163.1
• Gene: d4 / 35485
• FlyBaseID: FBgn0033015
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_006723470.1
• Gene: DPF1 / 8193
• HGNCID: 20225
• Length: 398
• Species: Homo sapiens
• Alignment Length: 504
• Identity: 167/504 - (33%)
• Similarity: 225/504 - (44%)
• Gaps: 158/504 - (31%)

  Fly    21 IQNFLND--KEKYKEILENSENFNTRLCIERRLRMPFLDPQTGVAQTHCSLFMKKKQRMPGLRHG 83
            |||.|..  ::.|:|.:|:..::|.|||.||.||:||||.||||||.:|.::|:|..|.|||..|
Human     5 IQNPLKSLGEDFYREAIEHCRSYNARLCAERSLRLPFLDSQTGVAQNNCYIWMEKTHRGPGLAPG 69

  Fly    84 QIYTYPSSRWRKPKRQYLLNPNQSFRAYQYR---EHNLQHSHHQTHQHHHHIPSSGVAVPQNPHL 145
            ||||||:..|||.:|..:|. :...|..:|:   |..|:...               .:|:.|.|
Human    70 QIYTYPARCWRKKRRLNILE-DPRLRPCEYKIDCEAPLKKEG---------------GLPEGPVL 118

  Fly   146 AESAAIAATDGNSMGASGDNDSKDSHANVEKEWFHD-EMDTSHFHHGDEFEDDFDSDNDFDESYT 209
             |:...|.|....:....:....|.......|:.|| |:        ::.|||.
Human   119 -EALLCAETGEKKIELKEEETIMDCQKQQLLEFPHDLEV--------EDLEDDI----------- 163

  Fly   210 SRGKRKKCSRPRRTNANVEGTPKRGRKG-----GGNRRKNAVEGESDR-------------KRRA 256
                      |||.|.         .||     ||.|::.......||             |.|.
Human   164 ----------PRRKNR---------AKGKAYGIGGLRKRQDTASLEDRDKPYVCDICGKRYKNRP 209

  Fly   257 GGNSANTSAAAAAAAAAVAHAACTAAAVASTGLYASHSNSASPIPINDDNSQSGLILPTNISSSY 321
            |                             ...:.:|::.|.  ...::|::.. .||.:..:::
Human   210 G-----------------------------LSYHYTHTHLAE--EEGEENAERH-ALPFHRKNNH 242

  Fly   322 DKTSSDAGASNDSIPLATMVAINAGLTTSNVCNAHPVQTGTNQTVFATGNKVKQRVERDIAQPSP 386
            .:...:..    .:|.|.              ..|..:...:.||.                |:.
Human   243 KQFYKELA----WVPEAQ--------------RKHTAKKAPDGTVI----------------PNG 273

  Fly   387 YCDFCLGDQRENKKTNMPEELVSCSDCGRSGHPSCLQFTANMIISVKRYRWQCIECKYCSICGTS 451
            |||||||.   :|||..||:|:||:||||||||||||||.||..:|:.|||||||||.||:||||
Human   274 YCDFCLGG---SKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTS 335

  Fly   452 DND----------DQLLFCDDCDRGYHMYCLSPPLVTPPEGSWSCKLCM 490
            :||          |||||||||||||||||||||:..||||||||.||:
Human   336 ENDGASWAGLTPQDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCL 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
d4	NP_610163.1	DPF1-3_N	31..93	CDD:464074	35/61 (57%)
		PHD1_d4	387..442	CDD:277091	38/54 (70%)
		PHD2_d4	444..489	CDD:277005	37/54 (69%)
DPF1	XP_006723470.1	DPF1-3_N	13..79	CDD:464074	35/65 (54%)
		SFP1	<186..220	CDD:227516	6/62 (10%)
		PHD1_DPF1	270..327	CDD:277160	40/75 (53%)
		PHD2_d4	328..383	CDD:277005	37/54 (69%)