Protein Alignment d4 and DPF1

DIOPT Version :9

• Sequence 1: NP_610163.1
• Gene: d4 / 35485
• FlyBaseID: FBgn0033015
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_011525658.1
• Gene: DPF1 / 8193
• HGNCID: 20225
• Length: 407
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 161/492 - (32%)
• Similarity: 210/492 - (42%)
• Gaps: 173/492 - (35%)

  Fly    31 YKEILENSENFNTRLCIERRLRMPFLDPQTGVAQTHCSLFMKKKQRMPGLRHGQIYTYPSSRWRK 95
            |:|.:|:..::|.|||.||.||:||||.||||||.:|.::|:|..|.|||..|||||||:..|||
Human    43 YREAIEHCRSYNARLCAERSLRLPFLDSQTGVAQNNCYIWMEKTHRGPGLAPGQIYTYPARCWRK 107

  Fly    96 PKRQYLLNPNQSFRAYQYR---EHNLQHSHHQTHQHHHHIPSSGVAVPQNPHLAESAAIAATDGN 157
            .:|..:|. :...|..:|:   |..|:...               .:|:.|.| |:...|.|...
Human   108 KRRLNILE-DPRLRPCEYKIDCEAPLKKEG---------------GLPEGPVL-EALLCAETGEK 155

  Fly   158 SMGASGDNDSKDSHANVEKEWFHD-EMDTSHFHHGDEFEDDFDSDNDFDESYTSRGKRKKCSRPR 221
            .:....:....|.......|:.|| |:        ::.|||.                     ||
Human   156 KIELKEEETIMDCQKQQLLEFPHDLEV--------EDLEDDI---------------------PR 191

  Fly   222 RTNANVEGTPKRGRKG-----GGNRRKNAVEGESDR-------------KRRAGGNSANTSAAAA 268
            |.|.         .||     ||.|::.......||             |.|.|
Human   192 RKNR---------AKGKAYGIGGLRKRQDTASLEDRDKPYVCDICGKRYKNRPG----------- 236

  Fly   269 AAAAAVAHAACTAAAVASTGLYASHSNSASPIPINDDNSQSGLILPTNISSSYDKTSSDAGASND 333
                              ...:.:|::.|                         :...:..|...
Human   237 ------------------LSYHYTHTHLA-------------------------EEEGEENAERH 258

  Fly   334 SIPLATMVAINAGLTTSNVCNAHPVQTGTNQTVFATGNKVKQRVERDIAQPSPYCDFCLGDQREN 398
            ::|....             |.|..:...:.||.                |:.|||||||.   :
Human   259 ALPFHRK-------------NNHKPKKAPDGTVI----------------PNGYCDFCLGG---S 291

  Fly   399 KKTNMPEELVSCSDCGRSGHPSCLQFTANMIISVKRYRWQCIECKYCSICGTSDND--------- 454
            |||..||:|:||:||||||||||||||.||..:|:.|||||||||.||:||||:||
Human   292 KKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDGASWAGLTP 356

  Fly   455 -DQLLFCDDCDRGYHMYCLSPPLVTPPEGSWSCKLCM 490
             |||||||||||||||||||||:..||||||||.||:
Human   357 QDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCL 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
d4	NP_610163.1	Requiem_N	30..98	CDD:290758	38/66 (58%)
		PHD1_d4	387..442	CDD:277091	38/54 (70%)
		PHD2_d4	444..489	CDD:277005	37/54 (69%)
DPF1	XP_011525658.1	Requiem_N	39..105	CDD:404861	35/61 (57%)
		SFP1	<212..246	CDD:227516	6/62 (10%)
		PHD1_DPF1	279..336	CDD:277160	40/75 (53%)
		PHD2_d4	337..392	CDD:277005	37/54 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156488
Domainoid	1	1.000	97	1.000	Domainoid score	I7254
eggNOG	1	0.900	-	-		E1_KOG1244
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2840
Isobase	1	0.950	-	0	Normalized mean entropy	S2732
OMA	1	1.010	-	-		QHG49768
OrthoDB	1	1.010	-	-		D312433at33208
OrthoFinder	1	1.000	-	-		FOG0001297
OrthoInspector	1	1.000	-	-		otm40575
orthoMCL	1	0.900	-	-		OOG6_105541
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5121
SonicParanoid	1	1.000	-	-		X895
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.740