Protein Alignment d4 and Dpf3

DIOPT Version :9

• Sequence 1: NP_610163.1
• Gene: d4 / 35485
• FlyBaseID: FBgn0033015
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_001254554.1
• Gene: Dpf3 / 70127
• MGIID: 1917377
• Length: 378
• Species: Mus musculus
• Alignment Length: 475
• Identity: 164/475 - (34%)
• Similarity: 223/475 - (46%)
• Gaps: 140/475 - (29%)

  Fly    31 YKEILENSENFNTRLCIERRLRMPFLDPQTGVAQTHCSLFMKKKQRMPGLRHGQIYTYPSSRWRK 95
            |||.:|:..::|:|||.||.:|:||||.||||||.:|.::|:|:.|.|||..||:||||:..|||
Mouse    17 YKEAIEHCRSYNSRLCAERSVRLPFLDSQTGVAQNNCYIWMEKRHRGPGLAPGQLYTYPARCWRK 81

  Fly    96 PKRQYLLNP--NQSFRAYQYREHNLQHSHHQTHQHHHHIPSSGVAVPQNPHLAESAAI-AATDGN 157
            .:|   |:|  :...|..:.:                  |...:.:.::...:||..: |...|.
Mouse    82 KRR---LHPPEDPKLRLLEIK------------------PEVELPLKKDGFTSESTTLEALLRGE 125

  Fly   158 SMGASGDNDSKDSHANVEKEWFHDEMDTSHFHHGDEFEDDFDSDNDFDESYTSRGKRKKCSRPRR 222
            .:....|...::|...:::...:||    :...|:| |:|.:.|..         |||..:|.|
Mouse   126 GVEKKVDAREEESIQEIQRVLENDE----NVEEGNE-EEDLEEDVP---------KRKNRTRGR- 175

  Fly   223 TNANVEGTPKRGRKGGGNRRKNAVEGESDR-----------KRRAGGNSANTSAAAAAAAAAVAH 276
                     .||..||..|...|.:.:.|:           |.|.|
Mouse   176 ---------ARGSAGGRRRHDAASQEDHDKPYVCDICGKRYKNRPG------------------- 212

  Fly   277 AACTAAAVASTGLYASHSNSASPIPINDDNSQSGLILPTNISSSYDKTSSDAGASNDSIPLATMV 341
                      ...:.:|::.||.   ..|.:|.            .:|.|.....|::
Mouse   213 ----------LSYHYAHTHLASE---EGDEAQD------------QETRSPPNHRNEN------- 245

  Fly   342 AINAGLTTSNVCNAHPVQTGTNQTVFATGNKVKQRVERDIAQPSPYCDFCLGDQRENKKTNMPEE 406
                          |..|.|.:.||.                |:.|||||||....|||:..|||
Mouse   246 --------------HRPQKGPDGTVI----------------PNNYCDFCLGGSNMNKKSGRPEE 280

  Fly   407 LVSCSDCGRSGHPSCLQFTANMIISVKRYRWQCIECKYCSICGTSDNDDQLLFCDDCDRGYHMYC 471
            ||||:||||||||:|||||.||..:||.|:|||||||.|.:||||:|||||||||||||||||||
Mouse   281 LVSCADCGRSGHPTCLQFTLNMTEAVKTYKWQCIECKSCILCGTSENDDQLLFCDDCDRGYHMYC 345

  Fly   472 LSPPLVTPPEGSWSCKLCME 491
            |:||:..||||||||.||.|
Mouse   346 LNPPVAEPPEGSWSCHLCWE 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
d4	NP_610163.1	Requiem_N	30..98	CDD:290758	37/66 (56%)
		PHD1_d4	387..442	CDD:277091	39/54 (72%)
		PHD2_d4	444..489	CDD:277005	35/44 (80%)
Dpf3	NP_001254554.1	Requiem_N	13..84	CDD:372894	37/66 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	146..193		18/70 (26%)
		SFP1	<195..222	CDD:227516	5/55 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	225..254		8/64 (13%)
		PHD1_DPF3	261..317	CDD:277162	40/55 (73%)
		PHD2_d4	318..363	CDD:277005	35/44 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846917
Domainoid	1	1.000	101	1.000	Domainoid score	I6910
eggNOG	1	0.900	-	-		E1_KOG1244
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2682
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49768
OrthoDB	1	1.010	-	-		D312433at33208
OrthoFinder	1	1.000	-	-		FOG0001297
OrthoInspector	1	1.000	-	-		otm42647
orthoMCL	1	0.900	-	-		OOG6_105541
Panther	1	1.100	-	-	LDO	PTHR10615
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5121
SonicParanoid	1	1.000	-	-		X895
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.890