DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment d4 and e(y)3

DIOPT Version :9

Sequence 1:	NP_610163.1	Gene:	d4 / 35485	FlyBaseID:	FBgn0033015	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001259719.1	Gene:	e(y)3 / 32965	FlyBaseID:	FBgn0087008	Length:	2012	Species:	Drosophila melanogaster

Alignment Length:	286	Identity:	78/286 - (27%)
Similarity:	120/286 - (41%)	Gaps:	76/286 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 DESYTSRGKRKKCSRPRRTNANVEGT-PKRGRKGGGNRRKNAVEGESDRKRRAGGNSANTSAAAA 268
            ||..||....|...:.:....:|..| |.|       |.:.:...::|:.|.|  :|::||:|.:
  Fly  1589 DEIKTSAPAPKDLGQEQSAIKSVTVTAPVR-------RSRRSTRQQTDKVRTA--SSSSTSSAQS 1644

  Fly   269 AAAAAVAHAACTAAAVASTGLYASHSNSASPIPINDDNSQSGLILPTNISSSYDKTSSDAGASND 333
            .::|                  :|.:.|:|.....|::..|.    |:..||....||.||:.::
  Fly  1645 VSSA------------------SSGNGSSSDTESGDESDFSS----TSSCSSSTGASSGAGSEDE 1687

  Fly   334 SIPLATMVAINAGLTTSNVCNAHPVQTGTNQTVFATGNKVKQRVERDIAQPSPYCDFCLGDQREN 398
            .               .|.|:: .|:..|                         |..||..|..|
  Fly  1688 D---------------GNECSS-SVRLST-------------------------CGVCLRSQHRN 1711

  Fly   399 KKTNMPEELVSCSDCGRSGHPSCLQFTANMIISVKRYRWQCIECKYCSICGTSDNDDQLLFCDDC 463
            .: :|||..:.|..|.:..||||:.....|:..|:.|.|||..||.|..|.:|....::|:|:.|
  Fly  1712 AR-DMPEAFIRCYTCRKRVHPSCVDMPPRMVGRVRNYNWQCAGCKCCIKCRSSQRPGKMLYCEQC 1775

  Fly   464 DRGYHMYCLSPPLVTPPEGSWSCKLC 489
            |||||:|||.  |.|.|:|.|||:.|
  Fly  1776 DRGYHIYCLG--LRTVPDGRWSCERC 1799

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
d4	NP_610163.1	Requiem_N	30..98	CDD:290758
		PHD1_d4	387..442	CDD:277091	20/54 (37%)
		PHD2_d4	444..489	CDD:277005	21/44 (48%)
e(y)3	NP_001259719.1	PHD_SF	1700..1754	CDD:304600	21/79 (27%)
		RanBP2-type Zn finger	1700..1725	CDD:275375	10/50 (20%)
		RanBP2-type Zn finger	1749..1775	CDD:275375	10/25 (40%)
		PHD2_PHF10	1756..1799	CDD:277004	21/44 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463884
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2732
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105037at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10615
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.990