Protein Alignment Atf6 and Creb3l4

DIOPT Version :9

• Sequence 1: NP_995745.1
• Gene: Atf6 / 35480
• FlyBaseID: FBgn0033010
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001007094.1
• Gene: Creb3l4 / 310616
• RGDID: 1359278
• Length: 367
• Species: Rattus norvegicus
• Alignment Length: 376
• Identity: 80/376 - (21%)
• Similarity: 143/376 - (38%)
• Gaps: 104/376 - (27%)

  Fly   124 SNVNGCSNEEAVYPLLVDSDKF-DPFFEPAKVR----SPNKEFNSTISNLSDIKNELPE--TSQD 181
            |.|.|....|        ||.| :.|.:|..:|    ||..:  |.:|  .|..:..|:  :|..
  Rat    31 SKVPGLQKSE--------SDDFLNLFIDPNMIRCSETSPGSD--SGVS--EDPGSPAPQAPSSPA 83

  Fly   182 LGFNSYNTSRNNSTLTKSWPI--NTELNLDNQVPKTVLPLSRTIY-LPSHDYKGLLPTV------ 237
            |....|.......|..::.|.  ...:.:|...|..::|.:.|:. |||..::.:||.|
  Rat    84 LYEVVYEAGALQGTQREAGPTFGLISIQIDQWSPAFMVPGACTVSDLPSEAHRHILPRVSTIAPP 148

  Fly   238 ------KCNGDRTLKKNVNVRSKISNIVIKKKNATFIQSLKESTPSH----TMDDKIYKKYQRMI 292
                  .|                ..:.:..:....:.....:.|||    ..:::|.||.:|.|
  Rat   149 PPAALLSC----------------QRLFLTDEEKHLLGQEGVTLPSHLPLTKAEERILKKIRRKI 197

  Fly   293 KNRESASLSRKKRKEYVVSLETRI-------NKLEKECDSLKAENITLRDQIFLLATSCQRESGN 350
            :|::||..||:::|||:..||:|:       .||:::...|:.:||:|..|:..|.
  Rat   198 RNKQSAQDSRRRKKEYIDGLESRVAACSEQNQKLQRKVQELERQNISLVAQVHQLQ--------- 253

  Fly   351 ANGLLHNYSGSERSENKNGRFTSKAKHCNKNNTTATIKKNVAILFAMAFVVSLNAGNFQKYLNIP 415
                               :||::........:|..:    .:||::|.::..:...||
  Rat   254 -------------------KFTAQTSSRAAQTSTCVL----ILLFSLALIILPSFSPFQ------ 289

  Fly   416 NNLEGKSEIEPVGKQL-SMSNRRLLWADSEEEYKEKNNLSTFLSGKQKEPS 465
            :..|.:||    |.|| .:.:|.:|..:...|..|...|...|....:.|:
  Rat   290 SQPEARSE----GYQLHGVISRNILTHEDMTESPESPVLKANLEELPQVPA 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atf6	NP_995745.1	bZIP_ATF6	287..338	CDD:269848	21/57 (37%)
		coiled coil	287..338	CDD:269848	21/57 (37%)
Creb3l4	NP_001007094.1	Required for transcriptional activation. /evidence=ECO:0000250	1..52		8/28 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	58..81		6/26 (23%)
		bZIP_CREB3	190..250	CDD:269837	22/59 (37%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	191..230		15/38 (39%)
		coiled coil	192..243	CDD:269837	17/50 (34%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	231..252		6/20 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338145
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840