Protein Alignment Atf6 and Creb3l2

DIOPT Version :9

• Sequence 1: NP_995745.1
• Gene: Atf6 / 35480
• FlyBaseID: FBgn0033010
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_848776.2
• Gene: Creb3l2 / 208647
• MGIID: 2442695
• Length: 521
• Species: Mus musculus
• Alignment Length: 515
• Identity: 107/515 - (20%)
• Similarity: 178/515 - (34%)
• Gaps: 172/515 - (33%)

  Fly    46 SELIPDLQKEAFGLHFSSNPITSEFSLSSPISGLKQIPSACSGEFKRNVNDNNFQLDLTNSRNDL 110
            |||:.:..:...| ...|:|..||.|.|..:......|:..            .|.:.:.|.::.
Mouse    37 SELLDEFSQNVLG-QLLSDPFLSEKSESMEVEPSPTSPAPL------------IQAEHSYSLSEE 88

  Fly   111 PEPNSSPTRSLNRSNVNGCSNEEAVYPLLVDSDKF-------------DPFFE-------PA--- 152
            |...|..|.:....:.|   :||      |:|:|:             :|..|       |:
Mouse    89 PRTQSPFTHAATSDSFN---DEE------VESEKWYLSTEFPSATIKTEPITEEQPPGLVPSVTL 144

  Fly   153 ----------KVRSP---NKEFNSTISNL-SDIKNELPETSQDLGFNSYNTSRNNSTLTKSWPIN 203
                      |..||   |...:|:...| ..||.|..|..|.|.|:....|.:...|..:.|.:
Mouse   145 TITAISTPFEKEESPLDMNAGGDSSCQTLIPKIKLEPHEVDQFLNFSPKEASVDQLHLPPTPPSS 209

  Fly   204 TELNLDNQV----------------PKTVLP-----LSRTIYLPS-HDYKGLLPTVKCNGD-RTL 245
            ...:.:..:                |...:|     ||.:..|.: |..:|..|.|....: |||
Mouse   210 HSSDSEGSLSPNPRLHPFSLSQAHSPARAMPRGPSALSTSPLLTAPHKLQGSGPLVLTEEEKRTL 274

  Fly   246 -KKNVNVRSKISNIVIKKKNATFIQSLKESTPSHTMDDKIYKKYQRMIKNRESASLSRKKRKEYV 309
             .:...:.:|:                    |....::|..||.:|.|||:.||..||:|:|||
Mouse   275 VAEGYPIPTKL--------------------PLTKSEEKALKKIRRKIKNKISAQESRRKKKEY- 318

  Fly   310 VSLETRINKLEKECDSLKAENITLRDQIFLLATSCQRESGNANGLLHNYSGSERSENKNGRFTSK 374
                  ::.|||:.:|...||:.||.::.:|                        ||.|.....:
Mouse   319 ------MDSLEKKVESCSTENLELRKKVEVL------------------------ENTNRTLLQQ 353

  Fly   375 ------------AKHCNKNNT-TATIKKNVAILFAMAFVVSLNAGNFQKY--------LNIPNNL 418
                        ::.|....| |.|....|.:.||:||     ...||.|        :.:|:.
Mouse   354 LQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAF-----GSFFQGYGPYPSATKMALPSQ- 412

  Fly   419 EGKSEIEPVGKQLSMS---NRRLLWADSEEEYKEKNNLSTF--LSGKQKEPSLYFLNSGI 473
                  .|:.:..:.|   :|.||..:.....:|.::.::.  |.|..:..||...:||:
Mouse   413 ------HPLSEPYTASVVRSRNLLIYEEHAPLEESSSPASAGELGGWDRGSSLLRASSGL 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atf6	NP_995745.1	bZIP_ATF6	287..338	CDD:269848	21/50 (42%)
		coiled coil	287..338	CDD:269848	21/50 (42%)
Creb3l2	NP_848776.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	83..106		5/25 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	196..264		10/67 (15%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	296..325		16/35 (46%)
		bZIP_CREB3	305..348	CDD:269837	19/73 (26%)
		coiled coil	305..348	CDD:269837	19/73 (26%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	336..357		6/44 (14%)
		S1P recognition. /evidence=ECO:0000250|UniProtKB:Q70SY1	427..430		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834559
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840