Protein Alignment Atf6 and CREB1

DIOPT Version :10

• Sequence 1: NP_995745.1
• Gene: Atf6 / 35480
• FlyBaseID: FBgn0033010
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_604391.1
• Gene: CREB1 / 1385
• HGNCID: 2345
• Length: 341
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 62/282 - (21%)
• Similarity: 109/282 - (38%)
• Gaps: 43/282 - (15%)

  Fly    72 LSSPISGLKQIPSACSGEFKRNVNDNNFQLDLTNSRNDLPEPNSSPTRSLNRSNVNGCSNEEAVY 136
            :.||  .::.:.|:|. :.||..:..  |:.......|..|...|.|.|..|..:  .|...:..
Human    78 IQSP--QVQTVQSSCK-DLKRLFSGT--QISTIAESEDSQESVDSVTDSQKRREI--LSRRPSYR 135

  Fly   137 PLLVDSDKFDPFFEPAKVRSPNKEFNSTISNLSDIKNELPETSQ------------DLGFNSYNT 189
            .:|.|.....|.....:.....:|.::.......:...:.:||.            .|..|..:.
Human   136 KILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDG 200

  Fly   190 SRNNSTLTKSWPINTELNLDNQVPKTVLPLSRT-----IYLPSHDYKGLLPTVKCNGD-RTLKKN 248
            .:...|||.:....|      |...|:|..::|     |.:||:.    :.....:|| :|.:..
Human   201 VQGLQTLTMTNAAAT------QPGTTILQYAQTTDGQQILVPSNQ----VVVQAASGDVQTYQIR 255

  Fly   249 VNVRSKISNIVIKKKNATFIQSLKESTPSHTMDDKIYKKYQRMIKNRESASLSRKKRKEYVVSLE 313
            ....|.|:..|        :.:...:.|:...::...|:..|::||||:|...|:|:||||..||
Human   256 TAPTSTIAPGV--------VMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLE 312

  Fly   314 TRINKLEKECDSLKAENITLRD 335
            .|:..||.:..:|..|...|:|
Human   313 NRVAVLENQNKTLIEELKALKD 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atf6	NP_995745.1	bZIP_ATF6	287..338	CDD:269848	21/49 (43%)
		coiled coil	287..338	CDD:269848	21/49 (43%)
CREB1	NP_604391.1	pKID	113..151	CDD:396650	9/39 (23%)
		bZIP_CREB1	285..339	CDD:269838	22/50 (44%)
		coiled coil	286..338	CDD:269838	21/49 (43%)