DRSC/TRiP Functional Genomics Resources

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Protein Alignment Atf6 and Atf1

DIOPT Version :9

Sequence 1:NP_995745.1 Gene:Atf6 / 35480 FlyBaseID:FBgn0033010 Length:741 Species:Drosophila melanogaster
Sequence 2:NP_031523.3 Gene:Atf1 / 11908 MGIID:1298366 Length:269 Species:Mus musculus


Alignment Length:346 Identity:76/346 - (21%)
Similarity:128/346 - (36%) Gaps:98/346 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 DINEYNLYNDLSLLGEVTENNYDNNIVHDILNSSAFYNDTSLDLSELIPDLQKEAFGLHFSSNPI 66
            |.::.|.....|..|......:.:.|||.:  ||...::.|.|.|:.|...|| |.|:       
Mouse     3 DSHKSNTTETASQPGSTVAGPHVSQIVHQV--SSLSESEESQDSSDSIGSSQK-AHGI------- 57

  Fly    67 TSEFSLSSPISGLKQIPSACSGEFKRNVNDNNFQLDLTNSRNDLPEPNSSPTRSLNRSNVNGCSN 131
                        |.:.||                     .|..|.:.:|..||.......|  .:
Mouse    58 ------------LARRPS---------------------YRKILKDLSSEDTRGRKGEGEN--PS 87

  Fly   132 EEAVYPLLVDSDKFDPFFEPAKVR----SPNKEFNSTISNLSDIKNELPETSQDLGFNSYNT-SR 191
            ..|:..:.|.:    |.::.:..:    :||...            :|...|.| |..:..| :.
Mouse    88 ISAITSMSVPA----PIYQTSSGQYIAIAPNGAL------------QLASPSTD-GVQALQTLTM 135

  Fly   192 NNSTLTKSWPINTELNLDNQVPKTVLPLSRT-----IYLPSHDYKGLLPTVKCNGDRTLKKNVNV 251
            .||:.|:.              .|:|..::|     |.:||:.    :.....:||   .:...:
Mouse   136 TNSSSTQQ--------------GTILQYAQTSDGQQILVPSNQ----VVVQTASGD---MQTYQI 179

  Fly   252 RSKISNIVIKKKNATFIQSLKESTPSHT--MDDKIYKKYQRMIKNRESASLSRKKRKEYVVSLET 314
            |:..|...:.:   |.:.:...:..|.|  .||...::..|::||||:|...|:|:||||..||.
Mouse   180 RTTPSATSLPQ---TVVMTSPVTLASQTTKTDDPQLRREIRLMKNREAARECRRKKKEYVKCLEN 241

  Fly   315 RINKLEKECDSLKAENITLRD 335
            |:..||.:..:|..|..||:|
Mouse   242 RVAVLENQNKTLIEELKTLKD 262

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Atf6NP_995745.1 bZIP_ATF6 287..338 CDD:269848 22/49 (45%)
coiled coil 287..338 CDD:269848 22/49 (45%)
Atf1NP_031523.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..90 26/131 (20%)
pKID 48..82 CDD:366954 13/74 (18%)
bZIP_CREB1 213..267 CDD:269838 22/50 (44%)
Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 213..237 11/23 (48%)
coiled coil 214..266 CDD:269838 22/49 (45%)
Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 239..260 7/20 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167834548
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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