Protein Alignment Atf6 and atf6

DIOPT Version :10

• Sequence 1: NP_995745.1
• Gene: Atf6 / 35480
• FlyBaseID: FBgn0033010
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_002933826.2
• Gene: atf6 / 100498199
• XenbaseID: XB-GENE-983814
• Length: 644
• Species: Xenopus tropicalis
• Alignment Length: 749
• Identity: 181/749 - (24%)
• Similarity: 280/749 - (37%)
• Gaps: 216/749 - (28%)

  Fly    33 NSSAFYNDTSL-DLSELIPDLQKEAFGLHFSSNPITSEFSLS---------------------SP 75
            :||.|...|.| |:..:.||.:.:.:|.||.:    .:|::.                     ||
 Frog    30 DSSLFEELTDLVDVDNMFPDEKNDLYGNHFDN----LDFNMDLMAWNTCPWDVPGDVIKLDPLSP 90

  Fly    76 ISGLKQIPS-------ACSGEFKRNVND-NNFQL-------DLTNSRNDLPEPNSSPTRSLNRSN 125
            .|.:..:||       |.|.:|....:| ::.||       |.:.|......|...|..|..::
 Frog    91 PSSISSVPSPSSVDSLASSSQFVPEDSDVSSSQLSPISLYSDCSKSPKSPDFPEEKPLISARQT- 154

  Fly   126 VNGCSNEEAVYPLLVDSDKFDPFFEPAKVRSPNKEFNSTISNLSDIKNELPETSQDLGFNSYNTS 190
             .|...:..:.|::.     .|..:|..:         .|...:||:.......:.:.|....|
 Frog   155 -TGSITQRKLPPVVP-----KPSIQPKAI---------IIPATADIQASATVAPKTIIFQPLTT- 203

  Fly   191 RNNSTLTKSWPINTELNLDNQ------VPKTV--LPLS-------------RTIYLPSHDYKGLL 234
                .|.|..|:.|.....:.      .|.||  ||.|             .|..:|:.....|.
 Frog   204 ----LLPKQQPLITLQQAPSAGQPVLLAPSTVVQLPASGIVTTQQVLTVGGGTATIPTSSMNILT 264

  Fly   235 PTV-KCNGDRTLKKNVNVRSKISNIVIKKKNATFIQSLKESTPSHTMDDKIYKKYQRMIKNRESA 298
            ||| :|             :|:|  .:|....|.:||:...|     |..:.::.||||||||||
 Frog   265 PTVPQC-------------AKMS--PVKPVMPTSVQSVDSGT-----DINVLRRQQRMIKNRESA 309

  Fly   299 SLSRKKRKEYVVSLETRINKLEKECDSLKAENITLRDQIFLLATSCQRESGNANGLLHNYSGSER 363
            ..||:|:|||:.:||.|:.....|.:.||.||.:|:..:..:.|
 Frog   310 FQSRRKKKEYMQTLEARLRVALSENERLKKENGSLQKLLEEVVT--------------------- 353

  Fly   364 SENKNGRFTSKAKHCNKNNTTATIKKNVAILFAMAFVVSLNAGNFQKYLNIPNNLEGKSEIE--P 426
             ||:            |...||..::.|.::...||::.    ||.. |:|..:..|..::|  |
 Frog   354 -ENQ------------KLKVTAPKRRAVCLMMVAAFLLL----NFSP-LSILESKPGSYDVEVSP 400

  Fly   427 VGKQLSMSNRRLLWADSEEEYKEKNNLSTFLSGKQKEPSLYFLNSGIRNHKINSFENITKNVSHT 491
            :     ..||.||...:.:|..|          .||.|      ...||.:..|.|.....|...
 Frog   401 I-----RHNRHLLGFSASDENVE----------AQKVP------DNTRNDRYISNEKALMVVKEP 444

  Fly   492 YSY-NEPPPLTYLSTRNCINRCRSHNGSSNQSKYFMLAQNLHKWISGTLNVSNFSKEKEDSNGFE 555
            ..| .:|||            |:.   ..|:::...|.|.|..||        ...|.|.:....
 Frog   445 LLYIPQPPP------------CQP---QVNKTQTLRLNQELRGWI--------HRHEVERTKSRR 486

  Fly   556 FFNNYFEEKRDIHIKHEKRKMFIDLNDYTSVLPEKQQKLNNTKSFE----NMREQINVISKIERR 616
            ..|::.|:|.:     ||..     |.....:......:.|:...:    :.|...:.:..|.||
 Frog   487 MTNSHKEQKPE-----EKSG-----NSELVTMQYTDTSIRNSNELQVYYYSPRSYQDFLEAIRRR 541

  Fly   617 DDTFYVFSFNMDHALLPALSYNSSYRPKLSLVLPLENPG---INGK--MKMIQVDCEVFNTKDFE 676
            :|||||.||..||.||||...|.:.|||:|::||..|..   |||:  ..|:|:||||.:|:...
 Frog   542 EDTFYVVSFRRDHLLLPATHRNKTTRPKMSIILPSTNVNDNVINGQDFEVMMQIDCEVMDTRILH 606

  Fly   677 VSHHLFPAKLRQNVIPRKPNKLNIKKSSTETPVS 710
            |.....|..||::    :.|:.|   |...:|.|
 Frog   607 VKASTIPPFLREH----RENQTN---SFYNSPTS 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atf6	NP_995745.1	bZIP_ATF6	287..338	CDD:269848	25/50 (50%)
		coiled coil	287..338	CDD:269848	25/50 (50%)
atf6	XP_002933826.2	SP1-4_N	<147..>300	CDD:425404	36/193 (19%)
		bZIP_ATF6	298..349	CDD:269848	25/50 (50%)
		coiled coil	298..349	CDD:269848	25/50 (50%)