Protein Alignment gus and SPSB4

DIOPT Version :9

• Sequence 1: NP_001246140.1
• Gene: gus / 35478
• FlyBaseID: FBgn0026238
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_543138.1
• Gene: SPSB4 / 92369
• HGNCID: 30630
• Length: 273
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 189/277 - (68%)
• Similarity: 221/277 - (79%)
• Gaps: 5/277 - (1%)

  Fly     1 MGQKISGGVKTVSRNDSQSTFKPIIPRELQ-ADFVKPARIDILLDMPPASRDLQLKHSWNSEDRS 64
            ||||:||.:|:|...  :...:| ..|||: |:..:|||:|.|||||.|...:||:|:||.||||
Human     1 MGQKLSGSLKSVEVR--EPALRP-AKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPEDRS 62

  Fly    65 LNIFVKEDDKLTFHRHPVAQSTDCIRGKVGLTKGLHIWEIYWPTRQRGTHAVVGVCTADAPLHSV 129
            ||:|||:||:|||||||||||||.||||||..:|||.|:|.||.|||||||||||.||.||||||
Human    63 LNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATARAPLHSV 127

  Fly   130 GYQSLVGSTEQSWGWDLGRNKLYHDSKNCAGVTYPAILKNDEAFLVPDKFLVALDMDEGTLSFIV 194
            ||.:||||..:||||||||::||||.||..||.|||.|..||||.:||..||.||||||||||||
Human   128 GYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIV 192

  Fly   195 DQQYLGIAFRGLRGKKLYPIVSAVWGHCEITMRYIGGLDPEPLPLMDLCRRTIRQKIGRTNLEEH 259
            |.||||:|||||:||||||:|||||||||:|||||.|||||||||||||||:||..:||..|::
Human   193 DGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDLCRRSIRSALGRQRLQD- 256

  Fly   260 IQQLQLPLSMKTYLLYK 276
            |..|.||.|:|.||.|:
Human   257 ISSLPLPQSLKNYLQYQ 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gus	NP_001246140.1	SPRY_SOCS1-2-4	56..229	CDD:293963	133/172 (77%)
		SOCS_SSB1_4	234..276	CDD:239688	25/41 (61%)
SPSB4	NP_543138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		13/35 (37%)
		SPRY_SOCS1-2-4	54..227	CDD:293963	133/172 (77%)
		SOCS	232..273	CDD:383010	25/41 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159052
Domainoid	1	1.000	211	1.000	Domainoid score	I2797
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H25315
Inparanoid	1	1.050	410	1.000	Inparanoid score	I1870
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48774
OrthoDB	1	1.010	-	-		D399707at33208
OrthoFinder	1	1.000	-	-		FOG0002660
OrthoInspector	1	1.000	-	-		otm40335
orthoMCL	1	0.900	-	-		OOG6_106110
Panther	1	1.100	-	-	LDO	PTHR12245
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4840
SonicParanoid	1	1.000	-	-		X1769
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800