Protein Alignment gus and SPSB3

DIOPT Version :10

• Sequence 1: NP_610158.3
• Gene: gus / 35478
• FlyBaseID: FBgn0026238
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: XP_005255730.1
• Gene: SPSB3 / 90864
• HGNCID: 30629
• Length: 410
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 76/295 - (25%)
• Similarity: 117/295 - (39%)
• Gaps: 61/295 - (20%)

  Fly    13 SRNDSQ-----STFKPIIPR------ELQADFVKPARIDILLDMPPASR---------DLQLKHS 57
            |.:||.     ||..|.||.      |...|....:.......:..|.|         |......
Human    97 SHSDSDSDPEYSTLPPSIPSAVPVTGESFCDCAGQSEASFCSSLHSAHRGRDCRCGEEDEYFDWV 161

  Fly    58 WNSEDRSLNIFVKEDD-KLTFHRHPVAQSTDCIRGKVGLTKGLHIWEIYWPTRQRGTHAVVGVCT 121
            |:..::|....:..|: |::||.. .:..|..|||...|.:|.|.|||...:...||..:||:.|
Human   162 WDDLNKSSATLLSCDNRKVSFHME-YSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGT 225

  Fly   122 ADAPL----HSVGYQSLVGSTEQSWGWDLGRNKLYHDSKNCAGVTYPAIL--KNDEA-----FLV 175
            :|..|    |:  :.||:|..|.||                 |::|..:|  |.|:.     |..
Human   226 SDVDLDKYRHT--FCSLLGRDEDSW-----------------GLSYTGLLHHKGDKTSFSSRFGQ 271

  Fly   176 PDKFLVALDMDEGTLSFIVDQQYLGIAFRGLRGKKLYPIV--SAVWGHCEITMRYIGGLDPEPLP 238
            .....|.||...|||:|..:::.:|:|...|:.|:.||:|  :|.....::|........
Human   272 GSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMVCSTAARSSMKVTRSCASATS----- 331

  Fly   239 LMDLCRRTIRQKIGRTNLEEHIQQLQLPLSMKTYL 273
            |..||...:||.  |.:..:.::.|.||..:|..|
Human   332 LQYLCCHRLRQL--RPDSGDTLEGLPLPPGLKQVL 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gus	NP_610158.3	SPRY_SOCS1-2-4	56..229	CDD:293963	52/186 (28%)
		SOCS_SSB1_4	234..276	CDD:239688	11/40 (28%)
SPSB3	XP_005255730.1	SPRY_SOCS3	159..341	CDD:293936	55/206 (27%)
		SOCS_SOCS_like	328..367	CDD:239687	11/44 (25%)