DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gus and Fsn

DIOPT Version :9

Sequence 1:	NP_001246140.1	Gene:	gus / 35478	FlyBaseID:	FBgn0026238	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_610849.1	Gene:	Fsn / 36460	FlyBaseID:	FBgn0043010	Length:	255	Species:	Drosophila melanogaster

Alignment Length:	177	Identity:	82/177 - (46%)
Similarity:	116/177 - (65%)	Gaps:	9/177 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 HSWNSEDRSLNIFVKEDDKLTFHRHPVAQSTDCIRGKVGLTKGLHIWEIYW--PTRQRGTHAVVG 118
            |:|:..|.|.|:::|.:. .|.||:|||||||..|||:|...|.|.||:.|  |.   ||.||:|
  Fly    81 HAWSPNDCSRNVYIKPNG-FTLHRNPVAQSTDAARGKIGFRHGRHTWEVIWEGPL---GTVAVIG 141

  Fly   119 VCTADAPLHSVGYQSLVGSTEQSWGWDLGRNKLYHDSKNCAGVTYPAILKNDEAFLVPDKFLVAL 183
            :.|.:|.|...||.:|:||.:|||||:|..|.|.|:. :..| :|| :|.|...:.|.::..|.|
  Fly   142 ISTKEAALQCHGYVALLGSDDQSWGWNLVENHLLHNG-DMQG-SYP-LLNNAPKYQVGERIRVIL 203

  Fly   184 DMDEGTLSFIVDQQYLGIAFRGLRGKKLYPIVSAVWGHCEITMRYIG 230
            |.::.||||..:.::||:|||||..|||||.||||:|:.|::|.|:|
  Fly   204 DCEDNTLSFEKNYEFLGVAFRGLPDKKLYPTVSAVYGNTEVSMVYLG 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gus	NP_001246140.1	SPRY_SOCS1-2-4	56..229	CDD:293963	80/174 (46%)
gus	NP_001246140.1	SOCS_SSB1_4	234..276	CDD:239688
Fsn	NP_610849.1	F-box-like	13..54	CDD:289689
Fsn	NP_610849.1	SPRY_Fbox	81..255	CDD:293964	82/177 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469107
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12245
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840