DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gus and Spsb3

DIOPT Version :9

Sequence 1:	NP_001246140.1	Gene:	gus / 35478	FlyBaseID:	FBgn0026238	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	XP_017452710.1	Gene:	Spsb3 / 302981	RGDID:	1310936	Length:	447	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	65/243 - (26%)
Similarity:	105/243 - (43%)	Gaps:	42/243 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 WNSEDRSLNIFVKEDD-KLTFHRHPVAQSTDCIRGKVGLTKGLHIWEIYWPTRQRGTHAVVGVCT 121
            |:..::|....:..|: |::||.. .:..|..|||...|..|.|.|||...:...||..:||:.|
  Rat   173 WDDLNKSSATLLSCDNRKVSFHME-YSCGTAAIRGTKELGDGQHFWEIKMTSPVYGTDMMVGIGT 236

  Fly   122 ADAPL----HSVGYQSLVGSTEQSWGWDLGRNKLYHDSKNCAGVTY-----------PAIL---- 167
            :|..|    |:  :.||:|..|.|||       |.:..:.|.|..:           |.:|
  Rat   237 SDVDLDKYHHT--FCSLLGRDEDSWG-------LSYTGRCCLGYGWGWQCHRPPRLTPLLLTGLL 292

  Fly   168 --KNDEA-----FLVPDKFLVALDMDEGTLSFIVDQQYLGIAFRGLRGKKLYPIVSAVWGHCEIT 225
              |.|:.     |.......|.||...|||:|..:::.:|:|...|:.::.||:|.:.  ..:.:
  Rat   293 HHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATRLQNRRFYPMVCST--AAKSS 355

  Fly   226 MRYIGGLDPEPLPLMDLCRRTIRQKIGRTNLEEHIQQLQLPLSMKTYL 273
            |:.|... .....|..||...:||.  |.:..:.::.|.||..:|..|
  Rat   356 MKVIRSC-ASSTSLQYLCCYRLRQL--RPDSGDTLEGLPLPPGLKQVL 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gus	NP_001246140.1	SPRY_SOCS1-2-4	56..229	CDD:293963	53/197 (27%)
gus	NP_001246140.1	SOCS_SSB1_4	234..276	CDD:239688	11/40 (28%)
Spsb3	XP_017452710.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810